McMillan Alison, Morrell Mary J
Sleep and Respiratory Dept, East and North Hertfordshire NHS Trust, Stevenage, UK.
Academic Unit of Sleep and Ventilation, National Heart and Lung Institute, Imperial College, London, UK; Respiratory Disease Biomedical Research Unit at the Royal Brompton Hospital and Harefield NHS Foundation Trust, London, UK.
Breathe (Sheff). 2016 Mar;12(1):50-60. doi: 10.1183/20734735.003216.
Sleep disordered breathing (SDB) is common and its prevalence increases with age. Despite this high prevalence, SDB is frequently unrecognised and undiagnosed in older people.There is accumulating evidence that SDB in older people is associated with worsening cardio- cerebrovascular, cognitive and functional outcomes.There is now good evidence to support the use of continuous positive airway pressure therapy in older patients with symptomatic SDB.
To highlight the prevalence and presentation of sleep disordered breathing (SDB) in older people.To inform readers about the risk factors for SDB in older people.To explore the impact of SDB in older people.To introduce current evidence based treatment options for SDB in older people. Sleep disordered breathing (SBD) increases in prevalence as we age, most likely due to physiological and physical changes that occur with ageing. Additionally, SDB is associated with comorbidity and its subsequent polypharmacy, which may increase with increasing age. Finally, the increased prevalence of SDB is intrinsically linked to the obesity epidemic. SDB is associated with serious outcomes in younger people and, likewise, older people. Thus, identification, diagnosis and treatment of SDB is important irrelevant of age. This article reviews the age-related changes contributing to SDB, the epidemiology and the risk factors for SDB in older people, the association of SDB with adverse outcomes, and diagnostic and treatment options for this population.
睡眠呼吸障碍(SDB)很常见,其患病率随年龄增长而增加。尽管患病率很高,但SDB在老年人中常常未被认识和诊断。越来越多的证据表明,老年人的SDB与心血管、认知和功能预后恶化有关。现在有充分的证据支持对有症状的老年SDB患者使用持续气道正压通气治疗。
强调老年人睡眠呼吸障碍(SDB)的患病率和表现。告知读者老年人SDB的危险因素。探讨SDB对老年人的影响。介绍老年人SDB目前基于证据的治疗选择。随着年龄的增长,睡眠呼吸障碍(SBD)的患病率会增加,这很可能是由于衰老过程中发生的生理和身体变化所致。此外,SDB与合并症及其随后的多种药物治疗有关,而多种药物治疗可能会随着年龄的增长而增加。最后,SDB患病率的增加与肥胖流行有着内在联系。SDB在年轻人和老年人中都与严重后果相关。因此,无论年龄大小,识别、诊断和治疗SDB都很重要。本文综述了导致SDB的与年龄相关的变化、老年人SDB的流行病学和危险因素、SDB与不良后果的关联以及该人群的诊断和治疗选择。