癌症患者的偶发性静脉血栓栓塞事件：2016年我们所了解的情况
Incidental venous thromboembolic events in cancer patients: what we know in 2016.
作者信息
Liebman Howard A, O'Connell Casey
机构信息
Jane Ann Nohl Division of Hematology and Center for the Study of Blood Diseases, University of California-Keck School of Medicine, Los Angeles, CA, USA.
Jane Ann Nohl Division of Hematology and Center for the Study of Blood Diseases, University of California-Keck School of Medicine, Los Angeles, CA, USA.
出版信息
Thromb Res. 2016 Apr;140 Suppl 1(Suppl 1):S18-20. doi: 10.1016/S0049-3848(16)30093-7.
Abstract
Cancer patients are at high risk of venous thromboembolism (VTE). Previous reports on the epidemiology and incident of thrombotic complications in cancer patients are based upon documented symptomatic events. However, the frequent use of contrast enhanced computerized tomography for cancer staging has documented a high incidence of unsuspected venous thrombosis (DVT), pulmonary embolism (PE) and abdominal visceral thrombosis in cancer patients. Recent studies focusing on the findings of incidental PE when compared to symptomatic PE find no significant difference in pulmonary distribution of clots, incidence of VTE recurrence or survival in these patients. Based upon these studies, current guidelines recommend treatment for incidental PE as recommended for symptomatic PE.
摘要
癌症患者发生静脉血栓栓塞（VTE）的风险很高。先前关于癌症患者血栓形成并发症的流行病学和发生率的报告是基于有症状事件的记录。然而，在癌症分期中频繁使用对比增强计算机断层扫描已证明，癌症患者中存在未被怀疑的静脉血栓形成（DVT）、肺栓塞（PE）和腹部内脏血栓形成的发生率很高。与有症状PE相比，近期针对偶然发现的PE的研究发现，这些患者的血栓在肺部的分布、VTE复发率或生存率并无显著差异。基于这些研究，目前的指南建议对偶然发现的PE采用与有症状PE相同的治疗方法。
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