Hausen B M, Jensen S, Mohnert J
Department of Dermatology, University Hospital, Hamburg, FRG.
Contact Dermatitis. 1989 Feb;20(2):133-43. doi: 10.1111/j.1600-0536.1989.tb03122.x.
The sensitizing capacity of 15 commercial colophony products was studied experimentally in guinea pigs. The study included 8 French and 6 American colophony derivatives as well as French tall oil colophony. The results indicate that tall oil colophony is the strongest sensitizing material within the tested group and that the maleic-modified products and the zinc-calcium-resinate are moderate sensitizers. Most of the modified products show a higher sensitizing capacity than the genuine resin acids themselves. Cross-reactions between the resin acids and the derivatives are uncommon. Therefore, patch testing with high concentrations of colophony (e.g., 60%) will not help to detect patients with colophony-derivative allergy.
在豚鼠身上通过实验研究了15种市售松香产品的致敏能力。该研究包括8种法国和6种美国的松香衍生物以及法国妥尔油松香。结果表明，在测试组中妥尔油松香是最强的致敏物质，马来酸改性产品和锌钙树脂酸盐是中度致敏剂。大多数改性产品比纯树脂酸本身表现出更高的致敏能力。树脂酸和衍生物之间的交叉反应并不常见。因此，用高浓度的松香（如60%）进行斑贴试验无助于检测对松香衍生物过敏的患者。
