Akyol Sumeyya, Gulec Mehmet Akif, Erdemli Haci Kemal, Akyol Omer
Department of Medical Biology, Turgut Ozal University Medical Faculty, Ankara, Turkey.
Department of Medical Biochemistry, Faculty of Medicine, Turgut Ozal University, Ankara, Turkey.
J Intercult Ethnopharmacol. 2016 Jan 28;5(1):105-7. doi: 10.5455/jice.20160127024542. eCollection 2016 Jan-Feb.
Propolis is a mixture having hundreds of polyphenols including caffeic acid phenethyl ester (CAPE). They have been using in several medical conditions/diseases in both in vitro and in vivo experimental setup. Cyclophosphamide (CP) has been used to treat a broad of malignancies including Hodgkin's and non-Hodgkin's lymphoma, Burkitt's lymphoma, chronic lymphocytic leukemia, Ewing's sarcoma, breast cancer, testicular cancer, etc. It may cause several side effects after treatment. In this mini review, the protective effects of propolis and CAPE were compared each other in terms of effectiveness against CP-induced injuries.
蜂胶是一种含有数百种多酚的混合物，包括咖啡酸苯乙酯（CAPE）。它们已被用于体外和体内实验装置中的多种医疗状况/疾病。环磷酰胺（CP）已被用于治疗多种恶性肿瘤，包括霍奇金淋巴瘤和非霍奇金淋巴瘤、伯基特淋巴瘤、慢性淋巴细胞白血病、尤因肉瘤、乳腺癌、睾丸癌等。治疗后它可能会引起多种副作用。在这篇小型综述中，就蜂胶和CAPE对CP诱导损伤的防护效果进行了相互比较。
