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增强深度成像与扫频源光学相干断层扫描在评估葡萄膜炎性青光眼-小柳原田病脉络膜厚度中的比较。

Comparison of Enhanced Depth Imaging and Swept Source Optical Coherence Tomography in Assessment of Choroidal Thickness in Vogt-Koyanagi-Harada Disease.

作者信息

Chee Soon-Phaik, Chan Shu-Wen Nicole, Jap Aliza

机构信息

a Singapore National Eye Centre , Singapore.

b Department of Ophthalmology , Yong Loo Lin School of Medicine, National University of Singapore , Singapore.

出版信息

Ocul Immunol Inflamm. 2017 Aug;25(4):528-532. doi: 10.3109/09273948.2016.1151896. Epub 2016 Apr 12.

DOI:10.3109/09273948.2016.1151896
PMID:27070488
Abstract

PURPOSE

To compare enhanced depth imaging (EDI-OCT) and swept source optical coherence tomography (SS-OCT) in assessment of Vogt-Koyanagi-Harada (VKH) disease.

METHODS

All consecutive VKH patients seen at Singapore National Eye Centre during 2012-2013 were imaged using both modalities. Subfoveal choroidal thickness (SFCT) was measured by one masked trained observer.

RESULTS

A total of 137 pairs of scans were obtained from 48 patients. SFCT was more likely to be measurable on SS-OCT than EDI-OCT (112, 81.8%; 84, 61.3%; p<0.001 Fisher's Exact test). There was good inter-OCT correlation of SFCT when both scans were measureable (mean of the difference in SFCT ± 2 standard deviations (SD) of -14.5 ± 21.0 μm).

CONCLUSIONS

SS-OCT images are superior to EDI-OCT but the SFCT measurements are comparable when both are readable.

摘要

目的

比较增强深度成像光学相干断层扫描(EDI - OCT)和扫频光学相干断层扫描(SS - OCT)在评估Vogt - 小柳 - 原田(VKH)病中的应用。

方法

对2012年至2013年期间在新加坡国立眼科中心就诊的所有连续性VKH患者使用这两种方式进行成像。由一名经过培训的遮眼观察者测量黄斑中心凹下脉络膜厚度(SFCT)。

结果

共从48例患者中获得137对扫描图像。与EDI - OCT相比,SS - OCT上更有可能测量到SFCT(112例,81.8%;84例,61.3%;Fisher精确检验,p<0.001)。当两次扫描均可测量时,SFCT在不同OCT之间具有良好的相关性(SFCT差异的平均值±2个标准差(SD)为-14.5±21.0μm)。

结论

SS - OCT图像优于EDI - OCT,但当两者均可读取时,SFCT测量结果具有可比性。

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