常规内镜检查对伯明翰地区T1期胃癌（早期胃癌）检出率的影响。

The effect of routine endoscopy on the detection rate of T1 gastric cancer (early gastric cancer) in Birmingham.

作者信息

Newbold K M, Thompson H, Dykes P W

机构信息

Department of Histopathology, General Hospital, Birmingham, United Kingdom.

出版信息

Endoscopy. 1989 Mar;21(2):56-9. doi: 10.1055/s-2007-1012900.

DOI:10.1055/s-2007-1012900

PMID:2707172

Abstract

The introduction of routine endoscopy facilities at the General Hospital, Birmingham has made no significant impact on the proportion of stage T1 or 'early' gastric cancers detected. Prior to this, T1 cancers comprised 2.8% of all tumors diagnosed, or 4.2% of resected cases. Following establishment of the service in 1974, 3.2% of all cases and 6.3% of those resected were stage T1 lesions. The clinical presentation reflected the high proportion of tumors associated with ulceration (67%). The accuracy rate for pre-operative diagnosis of a malignant lesion was barium meal 67%, cytology alone 73%, biopsy alone 80%, and cytology and biopsy in combination, repeated if suspicious, 100%. The crude survival rate at 5 years was 83.3% (age-adjusted 96%), and at 10 years 53.8%).

摘要

伯明翰综合医院引入常规内镜检查设备后，对T1期或“早期”胃癌的检出比例没有产生显著影响。在此之前，T1期癌症占所有确诊肿瘤的2.8%，或占切除病例的4.2%。1974年该服务建立后，所有病例中T1期病变占3.2%，切除病例中占6.3%。临床表现反映出与溃疡相关的肿瘤比例很高（67%）。术前诊断恶性病变的准确率为：钡餐检查67%，单纯细胞学检查73%，单纯活检80%，细胞学和活检联合检查（如有可疑重复检查）100%。5年粗生存率为83.3%（年龄调整后为96%），10年为53.8%。