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妊娠结局的流行病学数据统计分析。

Statistical analysis of epidemiologic data of pregnancy outcomes.

作者信息

Butler W J, Kalasinski L A

机构信息

Failure Analysis Associates, Palo Alto, CA 94303.

出版信息

Environ Health Perspect. 1989 Feb;79:223-7. doi: 10.1289/ehp.8979223.

Abstract

In this paper, a generalized logistic regression model for correlated observations is used to analyze epidemiologic data on the frequency of spontaneous abortion among a group of women office workers. The results are compared to those obtained from the use of the standard logistic regression model that assumes statistical independence among all the pregnancies contributed by one woman. In this example, the correlation among pregnancies from the same woman is fairly small and did not have a substantial impact on the magnitude of estimates of parameters of the model. This is due at least partly to the small average number of pregnancies contributed by each woman.

摘要

在本文中,一个用于相关观测值的广义逻辑回归模型被用于分析一组女性上班族自然流产频率的流行病学数据。将这些结果与使用标准逻辑回归模型所获得的结果进行比较,标准逻辑回归模型假定一名女性所有怀孕情况之间具有统计独立性。在这个例子中,同一女性怀孕情况之间的相关性相当小,并且对模型参数估计值的大小没有实质性影响。这至少部分是由于每位女性的平均怀孕次数较少。

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