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鳞状细胞癌和芽生菌病( Jorge Lobo病)

Squamous-cell carcinoma and lobomycosis (Jorge Lobo's disease).

作者信息

Baruzzi R G, Rodrigues D A, Michalany N S, Salomão R

机构信息

Division of Epidemiology, São Paulo Medical School, Brazil.

出版信息

Int J Dermatol. 1989 Apr;28(3):183-5. doi: 10.1111/j.1365-4362.1989.tb02459.x.

Abstract

Among the Cayabi Indians in Central Brazil, we found a high and unexpected prevalence of lobomycosis, which represents 21% of all the cases reported in the world medical literature until now. Most of the Cayabi patients have been observed for many years, and recently two developed cauliflower-like tumours in old lobomycosis scar lesions. The diagnosis of squamous cell carcinoma was confirmed histologically. In both cases, the tumor was surgically removed, but several months later tumors recurred in both patients. The appearance of squamous cell carcinoma in chronic scar lesions and ulcers of various etiologies has been reported by many authors, and should include lobomycosis.

摘要

在巴西中部的卡亚比印第安人中,我们发现芽生菌病的患病率高得出乎意料,占迄今为止世界医学文献报道的所有病例的21%。大多数卡亚比患者已被观察多年,最近有两名患者在陈旧的芽生菌病瘢痕病变处出现了菜花状肿瘤。经组织学检查确诊为鳞状细胞癌。在这两个病例中,肿瘤均通过手术切除,但数月后两名患者的肿瘤均复发。许多作者都报道过各种病因的慢性瘢痕病变和溃疡中出现鳞状细胞癌的情况,其中应包括芽生菌病。

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