雅司病中的浸润性鳞状细胞癌：两例报告并文献复习
Invasive squamous-cell carcinoma in Jorge Lobo's disease: Report of two cases and review of the literature.
作者信息
de Brito Arival Cardoso
机构信息
Service of Dermatology, Department of Dermatopathology, Federal University of Para (UFPA), Av. Generalíssimo Deodoro, 805 APT-302, CEP: 66050-160, Nazaré, Belem, Para, Brazil.
出版信息
Med Mycol Case Rep. 2022 May 20;37:13-16. doi: 10.1016/j.mmcr.2022.04.002. eCollection 2022 Sep.
Jorge Lobo's disease is a chronic granulomatous cutaneous-subcutaneous mycosis caused by the fungus , seen mainly in tropical and subtropical regions. Malignant transformation rarely occurs in this infection. In the present manuscript, we report two cases of Jorge Lobo's disease complicated by invasive squamous cell carcinoma: a 67-year-old man with a 26 -year history of Jorge Lobo's disease. In this case, the malignant tumor was surgically removed. The second case was a 75-year-old man with 22-year history of mycosis. In both patients the diagnosis of squamous cell carcinoma was confirmed by histopathological examination. There was no an immunocompromised state associated in these patients. The cases, diagnosis, complication, histopathologic findings of this disease are discussed.
约热·洛博病是一种由真菌引起的慢性肉芽肿性皮肤及皮下真菌病，主要见于热带和亚热带地区。这种感染很少发生恶变。在本手稿中，我们报告了两例并发侵袭性鳞状细胞癌的约热·洛博病病例：一例为一名67岁男性，有26年约热·洛博病病史。在该病例中，恶性肿瘤通过手术切除。第二例是一名75岁男性，有22年真菌病病史。两名患者的鳞状细胞癌诊断均经组织病理学检查证实。这些患者均无免疫功能低下状态。本文讨论了该疾病的病例、诊断、并发症及组织病理学表现。
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