Düe W, Pickartz H
Institute of Pathology, Klinikum Steglitz, Free University of Berlin, West Germany.
Int J Gynecol Pathol. 1989;8(1):46-53. doi: 10.1097/00004347-198903000-00006.
Disseminated peritoneal leiomyomatosis (DPL) is a rare clinicopathologic entity typically observed in women during pregnancy or immediately postpartum. Immunohistologic examinations of frozen as well as paraffin sections in three cases of DPL confirmed the myocytic character of the lesion and substantiated the hormonal influence on growth and regression of DPL nodules by detection of estrogen and progesterone receptors in the tumor cells. Implications of functional aspects as well as the benign clinical and morphologic feature of DPL are discussed in order to avoid inappropriate therapeutic measures.
播散性腹膜平滑肌瘤病(DPL)是一种罕见的临床病理实体,通常见于孕期或产后即刻的女性。对3例DPL的冰冻切片及石蜡切片进行免疫组织学检查,证实了病变的肌细胞特征,并通过检测肿瘤细胞中的雌激素和孕激素受体,证实了激素对DPL结节生长和消退的影响。为避免不恰当的治疗措施,本文讨论了DPL功能方面的意义以及其良性的临床和形态学特征。