MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, Budapest, Hungary.
Cardiac MR PET CT Program, Division of Cardiovascular Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Trends Cardiovasc Med. 2016 Aug;26(6):538-47. doi: 10.1016/j.tcm.2016.03.005. Epub 2016 Mar 15.
Vulnerable plaque is characterized by a large necrotic core and an overlying thin fibrous cap. Non-invasive imaging modalities such as computed tomography angiography (CTA) and magnetic resonance imaging (MRI) allow for the assessment of morphological plaque characteristics, while positron emission tomography (PET) enables the detection of metabolic activity within the atherosclerotic lesions. Invasive imaging modalities such as intravascular ultrasound (IVUS), optical-coherence tomography (OCT), and intravascular MRI (IV-MRI) display plaques at a high spatial resolution. Near-infrared spectroscopy (NIRS) allows for the detection of chemical components of atherosclerotic plaques. In this review, we describe state-of-the-art non-invasive and invasive imaging modalities and stress the combination of their advantages to identify vulnerable plaque features.
易损斑块的特征为大的坏死核心和薄的纤维帽覆盖。非侵入性成像方式如计算机断层血管摄影术（CTA）和磁共振成像（MRI）可以评估斑块的形态学特征，而正电子发射断层扫描（PET）可以检测动脉粥样硬化病变中的代谢活性。血管内超声（IVUS）、光相干断层扫描（OCT）和血管内 MRI（IV-MRI）等有创性成像方式可以以高空间分辨率显示斑块。近红外光谱（NIRS）可检测动脉粥样硬化斑块的化学组成。在这篇综述中，我们描述了最先进的非侵入性和侵入性成像方式，并强调了它们的优势相结合，以识别易损斑块的特征。
