Suppr超能文献

轻度创伤性脑损伤患者睡眠障碍的风险

The Risk of Sleep Disorder Among Persons with Mild Traumatic Brain Injury.

作者信息

Mollayeva Tatyana, Mollayeva Shirin, Colantonio Angela

机构信息

Acquired Brain Injury Lab, Rehabilitation Science Institute, University of Toronto, Toronto Rehabilitation Institute, 550 University Avenue, Rm 11207, Toronto, ON, M5G 2A2, Canada.

Department of Cell & Systems Biology, University of Toronto, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada.

出版信息

Curr Neurol Neurosci Rep. 2016 Jun;16(6):55. doi: 10.1007/s11910-016-0657-2.

Abstract

Sleep disorders and mild traumatic brain injury (mTBI) are among the most commonly occurring neurological problems clinicians encounter simultaneously. Each can cause the other, and both share common predisposing factors. An important question that remains to be addressed is whether high-risk groups can be defined. We observed an accumulation of considerable knowledge on sleep dysfunction in mTBI in recently published works. The results highlight sleep disturbances in mTBI as the product of diverse internal and external influences, acting on a genetically determined substrate. This may partially explain the clinical heterogeneity of mTBI, pointing to the importance of establishing an accurate history on the onset and course of a specific sleep disorder in the early stages post-mTBI in the individual patient. Such an approach will aid not only diagnosis and treatment but may also lead to identification of disorders whose symptoms mimic those of TBI and thereby direct the most suitable treatment and management.

摘要

睡眠障碍和轻度创伤性脑损伤(mTBI)是临床医生同时遇到的最常见的神经问题。两者可能相互引发,且存在共同的诱发因素。一个有待解决的重要问题是能否界定高危人群。我们注意到,近期发表的研究成果积累了大量关于mTBI患者睡眠功能障碍的知识。这些结果凸显出,mTBI患者的睡眠障碍是多种内部和外部影响作用于遗传决定的基质的产物。这可能部分解释了mTBI的临床异质性,表明在个体患者mTBI后的早期阶段,准确了解特定睡眠障碍的发病和病程史具有重要意义。这种方法不仅有助于诊断和治疗,还可能有助于识别那些症状与TBI相似的疾病,从而指导最适宜的治疗和管理。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验