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一种用于光谱X射线计算机断层扫描成像的基于加权多项式的材料分解方法。

A weighted polynomial based material decomposition method for spectral x-ray CT imaging.

作者信息

Wu Dufan, Zhang Li, Zhu Xiaohua, Xu Xiaofei, Wang Sen

机构信息

Key Laboratory of Particle & Radiation Imaging, Tsinghua University, Ministry of Education 100084 Beijing, People's Republic of China. Department of Engineering Physics, Tsinghua University 100084 Beijing, People's Republic of China.

出版信息

Phys Med Biol. 2016 May 21;61(10):3749-83. doi: 10.1088/0031-9155/61/10/3749. Epub 2016 Apr 15.

Abstract

Currently in photon counting based spectral x-ray computed tomography (CT) imaging, pre-reconstruction basis materials decomposition is an effective way to reconstruct densities of various materials. The iterative maximum-likelihood method requires precise spectrum information and is time-costly. In this paper, a novel non-iterative decomposition method based on polynomials is proposed for spectral CT, whose aim was to optimize the noise performance when there is more energy bins than the number of basis materials. Several subsets were taken from all the energy bins and conventional polynomials were established for each of them. The decomposition results from each polynomial were summed with pre-calculated weighting factors, which were designed to minimize the overall noises. Numerical studies showed that the decomposition noise of the proposed method was close to the Cramer-Rao lower bound under Poisson noises. Furthermore, experiments were carried out with an XCounter Filte X1 photon counting detector for two-material decomposition and three-material decomposition for validation.

摘要

当前,在基于光子计数的光谱X射线计算机断层扫描(CT)成像中,重建前的基材料分解是重建各种材料密度的有效方法。迭代最大似然法需要精确的光谱信息,且耗时较长。本文提出了一种基于多项式的新型非迭代分解方法用于光谱CT,其目的是在能量 bins 数量多于基材料数量时优化噪声性能。从所有能量 bins 中选取几个子集,并为每个子集建立常规多项式。每个多项式的分解结果与预先计算的加权因子相加,这些加权因子旨在最小化总体噪声。数值研究表明,在泊松噪声下,该方法的分解噪声接近克拉美罗下界。此外,使用XCounter Filte X1光子计数探测器进行了双材料分解和三材料分解的实验以进行验证。

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