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显微外科单侧椎板切开术治疗腰椎管狭窄症减压:长期结果及预测因素

Microsurgical unilateral laminotomy for decompression of lumbar spinal stenosis: long-term results and predictive factors.

作者信息

Schöller Karsten, Steingrüber Thomas, Stein Marco, Vogt Nina, Müller Tilman, Pons-Kühnemann Jörn, Uhl Eberhard

机构信息

Department of Neurosurgery, Justus-Liebig-University Giessen, Klinikstr. 33, 35392, Giessen, Germany.

Institute for Medical Informatics, Medical Statistics Study Group, Justus-Liebig-University, Giessen, Germany.

出版信息

Acta Neurochir (Wien). 2016 Jun;158(6):1103-13. doi: 10.1007/s00701-016-2804-6. Epub 2016 Apr 15.

Abstract

BACKGROUND

The microsurgical unilateral laminotomy (MUL) technique for bilateral decompression of lumbar spinal stenosis (LSS) is a less destabilizing alternative to laminectomy and leads to good short-term outcomes. However, little is known about the long-term results including predictive factors.

METHODS

Medical records of patients who underwent MUL for LSS decompression between 2005 and 2010 were reviewed, and a questionnaire was distributed to complement the long-term outcome data. The study population consisted of 176 patients including 17 patients with stable grade I spondylolisthesis. Complications and reoperations were meticulously analyzed. Clinical outcome was measured using a modified Prolo scale and was further dichotomized in good vs. poor outcome. Predictive factors were obtained from uni- and multivariate analyses.

RESULTS

The median age of the cohort was 70.0 years and the follow-up 71.7 months. Complications occurred in 5.1 % of the patients. The overall reoperation rate was 17.0 %, including surgery, which was exclusively performed at other levels in 4.0 %. The reoperation rate for fusion was 4.5 %. Good neurogenic claudication outcome faded from 98.3 % at hospital discharge to 47.2 % at 6 years. Multivariate analysis identified previous lumbar operation as a potential independent predictor of a reoperation; potential independent predictors of poor long-term claudication outcome were older age, female gender, higher body mass index (BMI) and tobacco smoking.

CONCLUSIONS

In our experience, the long-term reoperation rate after MUL for LSS is not negligible and higher in previously operated patients. It seems like the good initial clinical results after MUL may fade over time, and several patient-related predictive factors including potentially modifiable obesity and tobacco smoking seem to play an important role.

摘要

背景

用于双侧减压治疗腰椎管狭窄症(LSS)的显微外科单侧椎板切开术(MUL)技术,是一种比椎板切除术稳定性破坏更小的替代方法,且能带来良好的短期疗效。然而,对于包括预测因素在内的长期结果知之甚少。

方法

回顾了2005年至2010年间接受MUL治疗LSS减压的患者的病历,并发放问卷以补充长期结果数据。研究人群包括176例患者,其中17例为稳定的I级腰椎滑脱患者。对并发症和再次手术进行了细致分析。使用改良的普罗洛量表测量临床结果,并进一步分为良好与不良结果。通过单因素和多因素分析获得预测因素。

结果

队列的中位年龄为70.0岁,随访时间为71.7个月。5.1%的患者发生了并发症。总体再次手术率为17.0%,其中仅在其他节段进行的手术占4.0%。融合手术的再次手术率为4.5%。良好的神经源性间歇性跛行结果从出院时的98.3%降至6年时的47.2%。多因素分析确定既往腰椎手术是再次手术的潜在独立预测因素;长期间歇性跛行结果不良的潜在独立预测因素为年龄较大、女性、较高的体重指数(BMI)和吸烟。

结论

根据我们的经验,MUL治疗LSS后的长期再次手术率不可忽视,且既往接受过手术的患者更高。MUL术后良好的初始临床结果似乎会随时间推移而消退,包括潜在可改变的肥胖和吸烟在内的几个与患者相关的预测因素似乎起着重要作用。

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