Parmar Narendrasinh, Mohamed Mohamed, Elmoghrabi Adel, McCann Michael
Hurley Medical Center, Trauma Services-7W, One Hurley Plaza, Flint, MI 48439, United States.
Hurley Medical Center, Trauma Services-7W, One Hurley Plaza, Flint, MI 48439, United States.
Int J Surg Case Rep. 2016;23:40-3. doi: 10.1016/j.ijscr.2016.03.046. Epub 2016 Apr 2.
Eccrine porocarcinoma (EPC) is a rare malignancy of eccrine sweat glands. It is often seen during the sixth to eighth decades of life. We report the first case of eccrine porocarcinoma arising on the abdomen of a 21-year-old patient with ulcerative colitis.
A 21-Year-old female presented to emergency department with a one month history of an enlarging mass over left lower abdomen. Abdominal examination revealed a slightly erythematous, nodular and non-mobile firm mass in left lower quadrant. There was superficial ulceration with slight serous discharge. CT scan of the abdomen and pelvis with contrast revealed a superficial cystic lesion over the anterior abdominal wall, provisionally diagnosed as sebaceous cyst. Incision and drainage were performed and on follow-up, no signs of healing were observed and the patient subsequently underwent surgical excision. Histopathological examination revealed an eccrine porocarcinoma.
EPC is a rare and aggressive tumor. It may occur de novo or as a result of malignant transformation of an eccrine poroma. A long period of clinical history is often encountered. It usually occurs on the lower extremities followed by the, trunk, head and neck, and upper extremities. The clinical picture usually consists of a painless nodule or papule. Treatment is wide local excision. No strong evidence exists for adjuvant therapy. The risk of local recurrence is about 20%.
High index of suspicion is required for diagnosis of EPC. Early diagnosis is achieved by histopathological examination and early definitive surgical excision leads to excellent results.
小汗腺汗孔癌(EPC)是一种罕见的小汗腺恶性肿瘤。常见于60至80岁。我们报告首例发生在一名21岁溃疡性结肠炎患者腹部的小汗腺汗孔癌。
一名21岁女性因左下腹肿块增大1个月就诊于急诊科。腹部检查发现左下腹有一个略呈红斑状、结节状且固定不动的坚实肿块。有浅表溃疡并伴有少量浆液性分泌物。腹部和盆腔增强CT扫描显示前腹壁有一个浅表囊性病变,初步诊断为皮脂腺囊肿。进行了切开引流,随访时未见愈合迹象,患者随后接受了手术切除。组织病理学检查显示为小汗腺汗孔癌。
EPC是一种罕见且侵袭性的肿瘤。它可能原发出现,也可能由小汗腺汗孔瘤恶变而来。临床病史通常较长。它通常发生在下肢,其次是躯干、头颈部和上肢。临床表现通常为无痛性结节或丘疹。治疗方法是广泛局部切除。尚无有力证据支持辅助治疗。局部复发风险约为20%。
诊断EPC需要高度怀疑。通过组织病理学检查实现早期诊断,早期确定性手术切除可取得良好效果。