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海洋生物技术作为新型蛋白酶资源的开发及其在现代生物技术中的作用。

Development of marine biotechnology as a resource for novel proteases and their role in modern biotechnology.

作者信息

Homaei Ahmad, Lavajoo Fatemeh, Sariri Reyhaneh

机构信息

Department of Biochemistry, Faculty of Science, Hormozgan University, Bandar Abbas, Iran.

Department of Marine Biology, Faculty of Science, Hormozgan University, Bandar Abbas, Iran.

出版信息

Int J Biol Macromol. 2016 Jul;88:542-52. doi: 10.1016/j.ijbiomac.2016.04.023. Epub 2016 Apr 13.

DOI:10.1016/j.ijbiomac.2016.04.023
PMID:27086293
Abstract

Marine environment consists of the largest sources diversified genetic pool of material with an enormous potential for a wide variety of enzymes including proteases. A protease hydrolyzes the peptide bond and most of proteases possess many industrial applications. Marine proteases differ considerably from those found in internal or external organs of invertebrates and vertebrates. In common with all enzymes, external factors such as temperature, pH and type of media are important for the activity, catalytic efficiency, stability and proper functioning of proteases. In this review valuable characteristics of proteases in marine organisms and their applications are gathered from a wide literature survey. Considering their biochemical significance and their increasing importance in biotechnology, a thorough understanding of marine proteases functioning could be of prime importance.

摘要

海洋环境包含最大的多样化基因库,蕴藏着产生包括蛋白酶在内的多种酶的巨大潜力。蛋白酶可水解肽键,并且大多数蛋白酶具有许多工业应用。海洋蛋白酶与在无脊椎动物和脊椎动物的内部或外部器官中发现的蛋白酶有很大不同。与所有酶一样,诸如温度、pH值和培养基类型等外部因素对于蛋白酶的活性、催化效率、稳定性和正常功能很重要。在这篇综述中,通过广泛的文献调查收集了海洋生物中蛋白酶的宝贵特性及其应用。考虑到它们的生化意义以及它们在生物技术中日益增加的重要性,深入了解海洋蛋白酶的功能可能至关重要。

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