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腹腔镜胆囊切除术术中胆管造影:农村地区的一项临床试验。

Intraoperative cholangiogram during laparoscopic cholecystectomy: A clinical trial in rural setting.

作者信息

Verma Shreya, Wichmann Matthias W, Gunning Thomas, Beukes Eben, Maddern Guy

机构信息

Department of General Surgery, Mount Gambier Hospital, Mount Gambier, South Australia, Australia.

Division of Surgery, Queen Elizabeth Hospital, University of Adelaide, Woodville, South Australia, Australia.

出版信息

Aust J Rural Health. 2016 Dec;24(6):415-421. doi: 10.1111/ajr.12279. Epub 2016 Apr 17.

Abstract

OBJECTIVE

The routine use of intraoperative cholangiogram (IOC) in laparoscopic cholecystectomy (LC) remains a contentious issue. IOC helps to delineate biliary tree anatomy, prevent bile duct injury and image stones in the common bile duct (CBD). It may prove to be a valuable alternative to ERCP or MRCP, especially in the rural setting with limited resources.

DESIGN/SETTING/PARTICIPANTS/INTERVENTIONS/MAIN OUTCOME MEASURES: All patients undergoing laparoscopic cholecystectomy during a 12-month period were audited. For the first 6 months, patients were recruited for routine IOC and for the second 6 months, routine IOC was not performed. Cases were analysed with regard to patient demographics, operative details and clinical outcomes.

RESULTS

A total of 75 patients were analysed within the 12-month period. The majority were women aged 41-50. Ultrasound suggested common bile duct stones in 6.7% of cases. IOC was attempted in 50.7% of cases. Of these, 29 (76.3%) were successful. IOC added an average of 28 min to total theatre time. A total of 75% (n = 22) of IOCs showed normal flow of contrast into the intra- and extra-hepatic biliary systems. In 17% (n = 5) of patients, stones within the CBD were suspected, and these were referred for further management. ERCP/MRCP confirmed CBD stones in 60% (n = 3) of these patients. There was poor correlation between pre-operative suspicion and confirmed CBD stones (two patients only with pre-operative suspected CBD stone confirmed on IOC and ERCP). There were no operative complications related to IOC. There were no post-operative complications in cases where no IOC was done.

CONCLUSION

The majority of patients treated in our centre were women, middle-aged patients booked for elective laparoscopic cholecystectomy. Although only 6.7% cases were suspicious for CBD stones pre-operatively, a total of 17% of patients with routine IOC suggested CBD stones. IOC was found to be safe, taking only an additional 28 min of total theatre time. Routine rather than selective use of IOC could be considered to improve patient safety and long-term results.

摘要

目的

在腹腔镜胆囊切除术(LC)中常规使用术中胆管造影(IOC)仍是一个有争议的问题。IOC有助于描绘胆管树的解剖结构,预防胆管损伤,并对胆总管(CBD)内的结石进行成像。它可能被证明是内镜逆行胰胆管造影(ERCP)或磁共振胰胆管造影(MRCP)的一种有价值的替代方法,特别是在资源有限的农村地区。

设计/地点/参与者/干预措施/主要观察指标:对在12个月期间接受腹腔镜胆囊切除术的所有患者进行审计。在最初的6个月里,招募患者进行常规IOC,在接下来的6个月里,不进行常规IOC。对病例进行患者人口统计学、手术细节和临床结果分析。

结果

在12个月期间共分析了75例患者。大多数是41至50岁的女性。超声提示6.7%的病例有胆总管结石。50.7%的病例尝试进行IOC。其中,29例(76.3%)成功。IOC使总手术时间平均增加28分钟。总共75%(n = 22)的IOC显示造影剂正常流入肝内和肝外胆管系统。17%(n = 5)的患者怀疑有CBD结石,这些患者被转诊进行进一步治疗。ERCP/MRCP证实这些患者中有60%(n = 3)有CBD结石。术前怀疑与确诊的CBD结石之间相关性较差(只有2例术前怀疑CBD结石的患者在IOC和ERCP上得到证实)。没有与IOC相关的手术并发症。未进行IOC的病例没有术后并发症。

结论

在我们中心接受治疗的大多数患者是预定进行择期腹腔镜胆囊切除术的中年女性。虽然术前只有6.7%的病例怀疑有CBD结石,但常规IOC的患者中共有17%提示有CBD结石。发现IOC是安全的,仅使总手术时间增加28分钟。可以考虑常规而非选择性地使用IOC以提高患者安全性和长期效果。

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