Sugata Hisato, Hirata Masayuki, Yanagisawa Takufumi, Matsushita Kojiro, Yorifuji Shiro, Yoshimine Toshiki
Department of Neurosurgery, Osaka University Medical School, 2-2 Yamadaoka, Osaka, 565-0871, Japan.
Faculty of Welfare and Health Science, Oita University, 700 Dannoharu, Oita, 870-1192, Japan.
Sci Rep. 2016 Apr 19;6:24663. doi: 10.1038/srep24663.
The relationship between M1 activity representing motor information in real and imagined movements have not been investigated with high spatiotemporal resolution using non-invasive measurements. We examined the similarities and differences in M1 activity during real and imagined movements. Ten subjects performed or imagined three types of right upper limb movements. To infer the movement type, we used 40 virtual channels in the M1 contralateral to the movement side (cM1) using a beamforming approach. For both real and imagined movements, cM1 activities increased around response onset, after which their intensities were significantly different. Similarly, although decoding accuracies surpassed the chance level in both real and imagined movements, these were significantly different after the onset. Single virtual channel-based analysis showed that decoding accuracy significantly increased around the hand and arm areas during real and imagined movements and that these are spatially correlated. The temporal correlation of decoding accuracy significantly increased around the hand and arm areas, except for the period immediately after response onset. Our results suggest that cM1 is involved in similar neural activities related to the representation of motor information during real and imagined movements, except for presence or absence of sensory-motor integration induced by sensory feedback.
尚未使用非侵入性测量方法以高时空分辨率研究代表真实和想象运动中运动信息的M1活动之间的关系。我们研究了真实运动和想象运动期间M1活动的异同。10名受试者进行或想象了三种类型的右上肢运动。为了推断运动类型，我们使用波束形成方法，在运动侧对侧的M1（cM1）中使用40个虚拟通道。对于真实运动和想象运动，cM1活动在反应开始时左右增加，之后其强度有显著差异。同样，虽然真实运动和想象运动中的解码准确率都超过了机会水平，但在开始后这些准确率有显著差异。基于单个虚拟通道的分析表明，在真实运动和想象运动期间，手部和手臂区域周围的解码准确率显著提高，并且这些区域在空间上相关。除了反应开始后的 immediately after the onset，手部和手臂区域周围的解码准确率的时间相关性显著增加。我们的结果表明，cM1参与了与真实和想象运动中运动信息表征相关联的相似神经活动，除了由感觉反馈引起的感觉运动整合的存在与否。
