Tabasi Maryam, Mokhtari-Azad Talat, Eshraghian Mohammad Reza, Shadab Azadeh, Shatizadeh Somayeh, Shafiei-Jandaghi Nazanin Zahra, Yavarian Jila
School of Public Health, Tehran University of Medical Sciences.
Iran J Microbiol. 2016 Feb;8(1):80-4.
Human bocavirus (HBoV) is a newly discovered parvovirus. It has been detected primarily in children with acute respiratory tract infections. This study was conducted to clarify the frequency and genotype circulation pattern of HBoV in Iran.
Conventional PCR was performed on throat swabs of patients less than two years of age with respiratory illnesses during fall and winter 2012-2013.
HBoV virus DNA was detected in 15 of 140 samples (10.7 %). Sequencing and phylogenetic analysis on 5 samples showed that all were HBoV1. The positive samples were negative for influenza A and B viruses while co-infection with RSV was found in 2 (13.3%).
This study adds to the body of knowledge about the role of HBoV in acute respiratory illnesses in children in Iran.
人博卡病毒（HBoV）是一种新发现的细小病毒。它主要在患有急性呼吸道感染的儿童中被检测到。本研究旨在明确伊朗HBoV的感染频率和基因型流行模式。
对2012 - 2013年秋冬季节患有呼吸道疾病的2岁以下患者的咽拭子进行常规聚合酶链反应（PCR）检测。
140份样本中有15份（10.7%）检测到HBoV病毒DNA。对5份样本进行测序和系统发育分析表明，所有样本均为HBoV1。阳性样本中甲型和乙型流感病毒检测为阴性，而2份样本（13.3%）发现与呼吸道合胞病毒（RSV）共感染。
本研究增加了关于HBoV在伊朗儿童急性呼吸道疾病中作用的知识体系。
