Davis Gabrielle, Curtin Catherine M
Department of Surgery, Palo Alto VA, Suite 400, 770 Welch Road, Palo Alto, CA 94304, USA.
Department of Surgery, Palo Alto VA, Suite 400, 770 Welch Road, Palo Alto, CA 94304, USA; Division of Plastic Surgery, Stanford University, Suite 400, 770 Welch Road, Palo Alto, CA 94304, USA.
Hand Clin. 2016 May;32(2):257-62. doi: 10.1016/j.hcl.2015.12.011. Epub 2016 Feb 28.
Traumatic nerve injuries can be devastating and life-changing events, leading to functional morbidity and psychological stress and social constraints. Even in the event of a successful surgical repair with recovered motor function, pain can result in continued disability and poor quality of life. Pain after nerve injury can also prevent recovery and return to preinjury life. It is difficult to predict which patients will develop persistent pain; once incurred, pain can be even challenging to manage. This review seeks to define the types of pain following peripheral nerve injuries, investigate the pathophysiology and causative factors, and evaluate potential treatment options.
创伤性神经损伤可能是毁灭性的、改变生活的事件，会导致功能障碍、心理压力和社会限制。即使手术修复成功且运动功能恢复，疼痛仍可能导致持续的残疾和生活质量低下。神经损伤后的疼痛还可能阻碍恢复并回归到受伤前的生活状态。很难预测哪些患者会发展为持续性疼痛；一旦发生，疼痛的管理也颇具挑战性。本综述旨在明确周围神经损伤后的疼痛类型，研究其病理生理学和致病因素，并评估潜在的治疗选择。
