口腔舌鳞状细胞癌临床淋巴结阴性患者的隐匿性IV 期转移
Occult level IV metastases in clinically node-negative patients with oral tongue squamous cell carcinoma.
作者信息
Motiee-Langroudi M, Amali A, Saedi B, Emami H, Ensani F, Lotfi A, Rabbani Anari M
机构信息
Otorhinolaryngology Research Center,Otolaryngology Department,Tehran University of Medical Sciences,Iran.
Pathology Department,Tehran University of Medical Sciences,Iran.
出版信息
J Laryngol Otol. 2016 May;130(5):474-7. doi: 10.1017/S0022215116000931.
OBJECTIVE
The present study was conducted to determine the rate of level IV lymph node involvement among node-negative (N0) necks in patients with squamous cell carcinoma of the tongue.
METHODS
The study comprised 32 patients with squamous cell carcinoma of the tongue, with tumour-node-metastasis staging of T1-3N0M0, who were admitted to the Otolaryngology Department at Tehran University of Medical Sciences from March 2012 to March 2014. After a complete diagnostic evaluation, wide primary tumour excision (with 1.5-2 cm margins) and extended supraomohyoid neck dissection (levels I-IV) were accomplished.
RESULTS
Occult metastasis was found in 28 per cent of the patients. Level I, II and III metastases were the most common (18.75, 18.75 and 15.62 per cent, respectively). Level IV metastasis was found in 6.25 per cent of patients.
CONCLUSION
Supraomohyoid neck dissection appears to be an appropriate treatment for N0 tongue squamous cell carcinoma and there is no need for level IV lymph node dissection in a N0 patient.
目的
本研究旨在确定舌鳞状细胞癌患者中颈部淋巴结阴性（N0）患者的IV级淋巴结受累率。
方法
该研究纳入了32例舌鳞状细胞癌患者，肿瘤-淋巴结-转移分期为T1-3N0M0，于2012年3月至2014年3月入住德黑兰医科大学耳鼻喉科。经过全面的诊断评估后，完成了广泛的原发肿瘤切除（切缘为1.5 - 2厘米）和扩大的肩胛舌骨上颈部清扫术（I - IV级）。
结果
28%的患者发现隐匿性转移。I级、II级和III级转移最为常见（分别为18.75%、18.75%和15.62%）。6.25%的患者发现IV级转移。
结论
肩胛舌骨上颈部清扫术似乎是N0期舌鳞状细胞癌的合适治疗方法，N0患者无需进行IV级淋巴结清扫。
Zotero 插件