一名感染人类嗜T淋巴细胞病毒1型（HTLV-1）的女性因贝氏等孢球虫感染导致严重腹泻。
Severe Diarrhea Due To Cystoisospora belli Infection in an HTLV-1 Woman.
作者信息
Shafiei Reza, Najjari Mohsen, Kargar Kheirabad Ali, Hatam Golamreza
机构信息
Vector-borne Diseases Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran; Dept. of Parasitology and Mycology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Dept. of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
Iran J Parasitol. 2016 Jan-Mar;11(1):121-5.
Cystoisospora belli, formerly Isospora belli, as an opportunistic infection agent, is seen in immunocompromised patients like HTLV-1. We describe here cystoisosporiasis in an HTLV1 Iranian female in Mashhad, northwestern Iran in 2012 who presented with a debilitating diarrheal illness and great weight loss. C. belli was detected in her stool by modified acid-fast staining and then by molecular detection. Serologic testing was negative for HIV but she showed positivity for HTLV-1 infection. Treatment with TMP/SMX led to improvement of her diarrhea but she died after one year due to malabsorption syndrome. Adequate detection of C. belli diarrhea in immunocompromise patients of HTLV1 in endemic area can be cured by TMP/SMX.
贝氏等孢球虫，以前称为贝氏等孢子球虫，作为一种机会性感染病原体，见于如人类嗜T淋巴细胞病毒1型（HTLV-1）感染等免疫功能低下的患者。我们在此描述2012年在伊朗西北部马什哈德一名感染HTLV-1的伊朗女性发生的贝氏等孢球虫病，该患者出现使人衰弱的腹泻疾病并体重严重减轻。通过改良抗酸染色然后进行分子检测在其粪便中检测到贝氏等孢球虫。血清学检测HIV为阴性，但她显示HTLV-1感染呈阳性。用复方磺胺甲恶唑治疗使她的腹泻有所改善，但她在一年后因吸收不良综合征死亡。在流行地区，对HTLV-1免疫功能低下患者中贝氏等孢球虫性腹泻进行充分检测后可用复方磺胺甲恶唑治愈。
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