Nuernberg Gabriela L, Baeza Fernanda L, Fleck Marcelo P, Rocha Neusa S
Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Universidade Federal do Rio Grande do Sul, Porto Alegre RS , Brazil, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
Braz J Psychiatry. 2016 Apr 19;38(2):141-7. doi: 10.1590/1516-4446-2014-1643.
To describe and evaluate the response and predictors of remission during inpatient treatment in a psychiatric unit in a general hospital based on symptomatology, functionality, and quality of life (QoL).
Patients were admitted to a psychiatric unit in a tertiary general hospital in Brazil from June 2011 to December 2013 and included in the study if they met two of the severe mental illness (SMI) criteria: Global Assessment of Functioning (GAF) ≤ 50 and duration of service contact ≥ 2 years. Patients were assessed by the Brief Psychiatric Rating Scale (BPRS), the Clinical Global Impression (CGI) Severity Scale , GAF, the World Health Organization Quality of Life Instrument - Abbreviated version (WHOQOL-Bref), and specific diagnostic scales.
A total of 239 patients were included. BPRS mean scores were 25.54±11.37 at admission and 10.96±8.11 at discharge (p < 0.001). Patients with manic episodes (odds ratio: 4.03; 95% confidence interval: 1.14-14.30; p = 0.03) were more likely to achieve remission (CGI ≤ 2 at discharge) than those with depressive episodes. Mean length of stay was 28.95±19.86 days. All QoL domains improved significantly in the whole sample.
SMI patients had marked improvements in symptomatic and functional measures during psychiatric hospitalization. Patients with manic episodes had higher chance of remission according to the CGI.
基于症状学、功能及生活质量（QoL）描述并评估综合医院精神科住院治疗期间的缓解反应及预测因素。
2011年6月至2013年12月期间，患者被收治于巴西一家三级综合医院的精神科，若符合两项严重精神疾病（SMI）标准则纳入研究：功能总体评定量表（GAF）≤50且服务接触时长≥2年。采用简明精神病评定量表（BPRS）、临床总体印象（CGI）严重程度量表、GAF、世界卫生组织生活质量量表简版（WHOQOL-Bref）及特定诊断量表对患者进行评估。
共纳入239例患者。入院时BPRS平均评分为25.54±11.37，出院时为10.96±8.11（p<0.001）。与抑郁发作患者相比，躁狂发作患者更有可能实现缓解（出院时CGI≤2）（比值比：4.03；95%置信区间：1.14 - 14.30；p = 0.03）。平均住院时长为28.95±19.86天。整个样本的所有生活质量领域均有显著改善。
SMI患者在精神科住院期间症状及功能指标有显著改善。根据CGI，躁狂发作患者缓解的机会更高。
