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膀胱癌的热疗与放射治疗

Hyperthermia and radiotherapy in bladder cancer.

作者信息

Snider James William, Datta Niloy Ranjan, Vujaskovic Zeljko

机构信息

a Department of Radiation Oncology , University of Maryland Medical Center , Baltimore , Maryland , USA ;

b Department of Radiation Oncology, KSA-KSB, Kantonsspital Aarau , Aarau , Switzerland.

出版信息

Int J Hyperthermia. 2016 Jun;32(4):398-406. doi: 10.3109/02656736.2016.1150524. Epub 2016 Apr 20.

DOI:10.3109/02656736.2016.1150524
PMID:27097528
Abstract

Hyperthermia represents a unique, safe, and advantageous methodology for improving therapeutic strategies in the management of bladder cancer. This modality has shown promise in contributing to treatment regimens for both superficial and muscle-invasive disease. Especially in conjunction with intravesical chemotherapy, systemic therapy, and radiotherapy, hyperthermia shows particular synergistic benefit. As such, it should be explored further through clinical use and clinical trial in conjunction with currently available techniques and emerging technologies. However, to conceptualise the way forward, it is particularly important to understand the current challenges to widespread use of non-invasive, bladder-sparing approaches and the current state of bladder cancer care. As such, in the following article, we have focused on not only the rationale for concurrent radiotherapy and hyperthermia, but also the clinical landscape in bladder cancer as a whole.

摘要

热疗是一种独特、安全且具有优势的方法,可用于改善膀胱癌治疗策略。这种治疗方式在浅表性和肌层浸润性疾病的治疗方案中已显示出前景。特别是与膀胱内化疗、全身治疗和放疗联合使用时,热疗显示出特别的协同效益。因此,应结合当前可用技术和新兴技术,通过临床应用和临床试验进一步探索热疗。然而,为了构想未来的发展方向,了解非侵入性、保留膀胱方法广泛应用的当前挑战以及膀胱癌护理的现状尤为重要。因此,在以下文章中,我们不仅关注同步放疗和热疗的基本原理,还关注整个膀胱癌的临床情况。

相似文献

1
Hyperthermia and radiotherapy in bladder cancer.膀胱癌的热疗与放射治疗
Int J Hyperthermia. 2016 Jun;32(4):398-406. doi: 10.3109/02656736.2016.1150524. Epub 2016 Apr 20.
2
Effects of hyperthermia in neutralising mechanisms of drug resistance in non-muscle-invasive bladder cancer.热疗对非肌层浸润性膀胱癌耐药中和机制的影响
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Overview of bladder heating technology: matching capabilities with clinical requirements.膀胱加热技术概述:使功能与临床需求相匹配
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Chemohyperthermia in non-muscle-invasive bladder cancer: An overview of the literature and recommendations.非肌层浸润性膀胱癌的化疗热疗:文献综述与建议
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Intravesical radiofrequency-induced hyperthermia combined with chemotherapy for non-muscle-invasive bladder cancer.膀胱内射频诱导热疗联合化疗治疗非肌层浸润性膀胱癌
Int J Hyperthermia. 2016 Jun;32(4):351-62. doi: 10.3109/02656736.2016.1140232. Epub 2016 Feb 24.
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Hyperthermia as a treatment for bladder cancer.高温疗法治疗膀胱癌。
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[Intravesical instillations in non-muscle-invasive bladder cancer (NMIBC). Prospects for thermochemotherapy].[非肌层浸润性膀胱癌(NMIBC)的膀胱内灌注。热化疗的前景]
Prog Urol. 2016 Nov;26(14):860-864. doi: 10.1016/j.purol.2016.09.057. Epub 2016 Oct 3.
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Local microwave hyperthermia and intravesical chemotherapy as bladder sparing treatment for select multifocal and unresectable superficial bladder tumors.局部微波热疗联合膀胱内化疗作为特定多灶性及不可切除浅表性膀胱肿瘤的保膀胱治疗方法。
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Neoadjuvant combined microwave induced local hyperthermia and topical chemotherapy versus chemotherapy alone for superficial bladder cancer.新辅助联合微波诱导局部热疗与局部化疗对比单纯化疗治疗浅表性膀胱癌
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10
Is hyperthermia combined with radiotherapy adequate in elderly patients with muscle-invasive bladder cancers? Thermo-radiobiological implications from an audit of initial results.热疗联合放疗对老年肌层浸润性膀胱癌患者是否足够?对初步结果审核的热放射生物学意义。
Int J Hyperthermia. 2016 Jun;32(4):390-7. doi: 10.3109/02656736.2015.1132340. Epub 2016 Jan 22.

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Molecules. 2023 Mar 29;28(7):3053. doi: 10.3390/molecules28073053.
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A practical approach to bladder preservation with hypofractionated radiotherapy for localised muscle-invasive bladder cancer.一种采用大分割放疗对局限性肌层浸润性膀胱癌进行膀胱保留的实用方法。
Clin Transl Radiat Oncol. 2021 Aug 8;31:1-7. doi: 10.1016/j.ctro.2021.08.003. eCollection 2021 Nov.
3
Integrating Loco-Regional Hyperthermia Into the Current Oncology Practice: SWOT and TOWS Analyses.
将局部区域热疗纳入当前肿瘤学实践:SWOT分析和TOWS分析
Front Oncol. 2020 Jun 12;10:819. doi: 10.3389/fonc.2020.00819. eCollection 2020.
4
A Pilot Study of Radiotherapy and Local Hyperthermia in Elderly Patients With Muscle-Invasive Bladder Cancers Unfit for Definitive Surgery or Chemoradiotherapy.老年肌层浸润性膀胱癌患者放疗与局部热疗的初步研究,这些患者不适合进行根治性手术或放化疗。
Front Oncol. 2019 Sep 10;9:889. doi: 10.3389/fonc.2019.00889. eCollection 2019.