Dept. of Medical Biophysics, Schulich School of Medicine and Dentistry, University of Western Ontario, 1151 Richmond St, London, ON, Canada.
Dept. of Medical Imaging, Schulich School of Medicine and Dentistry, University of Western Ontario, 1151 Richmond St, London, ON, Canada.
Comput Med Imaging Graph. 2016 Jul;51:11-9. doi: 10.1016/j.compmedimag.2016.02.002. Epub 2016 Apr 8.
Automatic vertebra recognition, including the identification of vertebra locations and naming in multiple image modalities, are highly demanded in spinal clinical diagnoses where large amount of imaging data from various of modalities are frequently and interchangeably used. However, the recognition is challenging due to the variations of MR/CT appearances or shape/pose of the vertebrae. In this paper, we propose a method for multi-modal vertebra recognition using a novel deep learning architecture called Transformed Deep Convolution Network (TDCN). This new architecture can unsupervisely fuse image features from different modalities and automatically rectify the pose of vertebra. The fusion of MR and CT image features improves the discriminativity of feature representation and enhances the invariance of the vertebra pattern, which allows us to automatically process images from different contrast, resolution, protocols, even with different sizes and orientations. The feature fusion and pose rectification are naturally incorporated in a multi-layer deep learning network. Experiment results show that our method outperforms existing detection methods and provides a fully automatic location+naming+pose recognition for routine clinical practice.
自动脊椎识别,包括在多个图像模态中识别脊椎位置和命名,在脊柱临床诊断中需求很高,因为经常使用来自各种模态的大量成像数据,并且可以互换使用。然而,由于 MR/CT 外观或脊椎形状/姿势的变化,识别具有挑战性。在本文中,我们提出了一种使用称为变换深度卷积网络(TDCN)的新型深度学习架构进行多模态脊椎识别的方法。这个新的架构可以对来自不同模态的图像特征进行无监督融合,并自动矫正脊椎的姿势。MR 和 CT 图像特征的融合提高了特征表示的辨别力,并增强了脊椎模式的不变性,这使我们能够自动处理来自不同对比度、分辨率、协议的图像,甚至可以处理大小和方向不同的图像。特征融合和姿势矫正自然地包含在多层深度学习网络中。实验结果表明,我们的方法优于现有的检测方法,为常规临床实践提供了全自动的定位+命名+姿势识别。