Bock Jens-Oliver, Brettschneider Christian, Weyerer Siegfried, Werle Jochen, Wagner Michael, Maier Wolfgang, Scherer Martin, Kaduszkiewicz Hanna, Wiese Birgitt, Moor Lilia, Stein Janine, Riedel-Heller Steffi G, König Hans-Helmut
Department of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Department of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
J Affect Disord. 2016 Jul 15;199:139-47. doi: 10.1016/j.jad.2016.04.008. Epub 2016 Apr 12.
The study aimed at determining excess costs of late-life depression from a societal perspective. Moreover, the impact of recognition of depression by GPs on costs was investigated.
Cross-sectional data were obtained from a large multicenter observational cohort study (AgeMooDe). Participants (n=1197) aged 75 years or older and were recruited via their GPs in Leipzig, Bonn, Hamburg, and Mannheim in Germany from May 2012 until December 2013. In the base case analysis, depression was assessed using the Geriatric Depression Scale (GDS; cutoff GDS≥6). Data on health care utilization and costs were based on participants' self-reports for inpatient treatment, outpatient treatment, pharmaceuticals, and formal and informal nursing care.
Unadjusted mean costs in a six-month period for depressed individuals (€5031) exceeded those of non-depressed (€2700) by the factor 1.86 and were higher in all health care sectors considered. Statistically significant positive excess costs persisted in all formal health care sectors after adjusting for comorbidity and socio-demographics. Recognition of depression by the GP did not moderate the relationship of depression and health care costs.
Analyses were restricted to a cross-sectional design, not permitting any conclusions on causal interference of the variables considered.
The findings stress the enormous burden of depression in old age for all sectors of the health care system. The fact that GPs' recognition of depression does not moderate the relationship between depression and costs adds further insights into the economics of this frequent psychiatric disorder.
本研究旨在从社会角度确定晚年抑郁症的额外成本。此外,还调查了全科医生对抑郁症的识别对成本的影响。
横断面数据来自一项大型多中心观察性队列研究(AgeMooDe)。研究对象为年龄在75岁及以上的参与者(n = 1197),于2012年5月至2013年12月期间通过德国莱比锡、波恩、汉堡和曼海姆的全科医生招募。在基础病例分析中,使用老年抑郁量表(GDS;临界值GDS≥6)评估抑郁症。医疗保健利用和成本数据基于参与者对住院治疗、门诊治疗、药品以及正式和非正式护理的自我报告。
在六个月期间,抑郁症患者的未调整平均成本(5031欧元)比非抑郁症患者(2700欧元)高出1.86倍,且在所考虑的所有医疗保健部门中都更高。在调整了合并症和社会人口统计学因素后,所有正式医疗保健部门的统计学显著正额外成本仍然存在。全科医生对抑郁症的识别并未缓和抑郁症与医疗保健成本之间的关系。
分析仅限于横断面设计,无法就所考虑变量的因果干扰得出任何结论。
研究结果强调了老年抑郁症给医疗保健系统各部门带来的巨大负担。全科医生对抑郁症的识别并未缓和抑郁症与成本之间的关系这一事实,为这种常见精神疾病的经济学提供了进一步的见解。