Biswas Ahitagni, Julka Pramod Kumar
Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India.
Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India.
J Egypt Natl Canc Inst. 2016 Jun;28(2):129-32. doi: 10.1016/j.jnci.2016.04.002. Epub 2016 Apr 19.
Bleomycin induced flagellate dermatitis is an uncommon and unique adverse effect. With the declining use of bleomycin, this complication is becoming increasingly infrequent in day-to-day clinical practice. We herein describe a case of a 13year old male patient with left thalamic mixed germ cell tumour treated by multimodality approach, who developed flagellate erythema after two cycles of combination chemotherapy with bleomycin, etoposide and cisplatin (BEP). This brief report highlights the importance of awareness and timely identification and management of this dermatological toxicity in patients undergoing bleomycin based combination chemotherapy.
博来霉素诱发的鞭毛虫样皮炎是一种罕见且独特的不良反应。随着博来霉素使用的减少，这种并发症在日常临床实践中越来越不常见。我们在此描述一例13岁男性左丘脑混合性生殖细胞肿瘤患者，采用多模式方法治疗，在接受博来霉素、依托泊苷和顺铂（BEP）联合化疗两个周期后出现鞭毛虫样红斑。本简短报告强调了在接受基于博来霉素的联合化疗的患者中，认识、及时识别和处理这种皮肤毒性的重要性。
