de Vries J, Graf M, Scheremet R, Troetschler H
Department of General Neurosurgery, University of Freiburg, Germany.
Clin Neurol Neurosurg. 1994 Feb;96(1):58-65. doi: 10.1016/0303-8467(94)90031-0.
A 62-year-old woman presented with a convexity meningioma which, after primary surgery, was histopathologically graded as grade II. There followed three more operations due to repeated rapid local recurrences. After each of these three operations histology revealed dedifferentiated grade III tumors. At third recurrence moreover, other multiple tumor masses in the vicinity of the primary tumor site and in the lung were found. These had the same histological appearance as the local recurrences. The patient died 30 months after primary surgery from respiratory failure due to the multiple lung metastases.
一名62岁女性因凸面脑膜瘤就诊，初次手术后，组织病理学分级为II级。由于肿瘤反复快速局部复发，又进行了三次手术。这三次手术后的组织学检查均显示为去分化的III级肿瘤。此外，在第三次复发时，在原发肿瘤部位附近及肺部发现了其他多个肿瘤肿块。这些肿块的组织学表现与局部复发灶相同。患者在初次手术后30个月因多发肺转移导致呼吸衰竭死亡。
