Kawaguchi Takumi, Suetsugu Takuro, Ogata Shyou, Imanaga Minami, Ishii Kumiko, Esaki Nao, Sugimoto Masako, Otsuyama Jyuri, Nagamatsu Ayu, Taniguchi Eitaro, Itou Minoru, Oriishi Tetsuharu, Iwasaki Shoko, Miura Hiroko, Torimura Takuji
Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka 830-0011, Japan.
Department of Nursing, Kurume University Hospital, Kurume, Fukuoka 830-0011, Japan.
Biomed Rep. 2016 May;4(5):615-622. doi: 10.3892/br.2016.640. Epub 2016 Mar 23.
The incidence of traffic accidents in patients with chronic liver disease (CLD) is high in the USA. However, the characteristics of patients, including dietary habits, differ between Japan and the USA. The present study investigated the incidence of traffic accidents in CLD patients and the clinical profiles associated with traffic accidents in Japan using a data-mining analysis. A cross-sectional study was performed and 256 subjects [148 CLD patients (CLD group) and 106 patients with other digestive diseases (disease control group)] were enrolled; 2 patients were excluded. The incidence of traffic accidents was compared between the two groups. Independent factors for traffic accidents were analyzed using logistic regression and decision-tree analyses. The incidence of traffic accidents did not differ between the CLD and disease control groups (8.8 vs. 11.3%). The results of the logistic regression analysis showed that yoghurt consumption was the only independent risk factor for traffic accidents (odds ratio, 0.37; 95% confidence interval, 0.16-0.85; P=0.0197). Similarly, the results of the decision-tree analysis showed that yoghurt consumption was the initial divergence variable. In patients who consumed yoghurt habitually, the incidence of traffic accidents was 6.6%, while that in patients who did not consume yoghurt was 16.0%. CLD was not identified as an independent factor in the logistic regression and decision-tree analyses. In conclusion, the difference in the incidence of traffic accidents in Japan between the CLD and disease control groups was insignificant. Furthermore, yoghurt consumption was an independent negative risk factor for traffic accidents in patients with digestive diseases, including CLD.
在美国,慢性肝病(CLD)患者的交通事故发生率较高。然而,日本和美国患者的特征(包括饮食习惯)存在差异。本研究采用数据挖掘分析方法,调查了日本CLD患者的交通事故发生率以及与交通事故相关的临床特征。进行了一项横断面研究,纳入了256名受试者[148名CLD患者(CLD组)和106名其他消化系统疾病患者(疾病对照组)];排除了2名患者。比较了两组之间的交通事故发生率。使用逻辑回归和决策树分析来分析交通事故的独立因素。CLD组和疾病对照组之间的交通事故发生率没有差异(8.8%对11.3%)。逻辑回归分析结果显示,食用酸奶是交通事故的唯一独立危险因素(比值比,0.37;95%置信区间,0.16 - 0.85;P = 0.0197)。同样,决策树分析结果显示,食用酸奶是初始分歧变量。习惯性食用酸奶的患者中,交通事故发生率为6.6%,而未食用酸奶的患者中这一发生率为16.0%。在逻辑回归和决策树分析中,CLD未被确定为独立因素。总之,在日本,CLD组和疾病对照组之间的交通事故发生率差异不显著。此外,食用酸奶是包括CLD在内的消化系统疾病患者发生交通事故的独立负性危险因素。