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住院寻求庇护者中传染病和耐药微生物的高流行率;截至2015年9月未发现产碳青霉烯酶肠杆菌科细菌。

High Prevalence of Infectious Diseases and Drug-Resistant Microorganisms in Asylum Seekers Admitted to Hospital; No Carbapenemase Producing Enterobacteriaceae until September 2015.

作者信息

Ravensbergen Sofanne J, Lokate Mariëtte, Cornish Darren, Kloeze Eveline, Ott Alewijn, Friedrich Alex W, van Hest Rob, Akkerman Onno W, de Lange Wiel C, van der Werf Tjip S, Bathoorn Erik, Stienstra Ymkje

机构信息

Department of Internal Medicine/Infectious Diseases, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.

Department of Medical Microbiology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.

出版信息

PLoS One. 2016 May 4;11(5):e0154791. doi: 10.1371/journal.pone.0154791. eCollection 2016.

Abstract

INTRODUCTION

The current refugee crisis emphasizes the need for information on infectious diseases and resistant microorganisms in asylum seekers with possible consequences for public health and infection control.

METHODS

We collected data from asylum seekers admitted to our university hospital or who presented at the Emergency Department (n = 273). We collected general and demographic characteristics including country of origin, the reason of presentation, and the screening results of multi-drug resistant organisms.

RESULTS

67% of the patients were male with a median age of the study group of 24 years (IQR 15-33); 48% of the patients had an infectious disease-predominantly malaria with P. vivax or tuberculosis. Patients also reported with diseases which are less common-e.g. leishmaniasis, or even conditions rarely diagnosed in Europe-e.g. louse borne relapsing fever. A carriage rate of 31% for multi-drug resistant microorganisms (MDRO) was observed, with ESBL-expressing E.coli (n = 20) being the most common MDRO. No carriage of Carbapenemase Producing Enterobacteriaceae was found.

CONCLUSION

The current refugee crisis in Europe challenges hospitals to quickly identify and respond to communicable diseases and the carriage of MDRO. A rapid response is necessary to optimize the treatment of infectious diseases amongst asylum seekers to maximize infection control.

摘要

引言

当前的难民危机凸显了获取寻求庇护者传染病和耐药微生物信息的必要性,这些信息可能对公共卫生和感染控制产生影响。

方法

我们收集了入住我校附属医院或前往急诊科就诊的寻求庇护者的数据(n = 273)。我们收集了一般和人口统计学特征,包括原籍国、就诊原因以及多重耐药菌的筛查结果。

结果

67%的患者为男性,研究组的中位年龄为24岁(四分位间距15 - 33岁);48%的患者患有传染病,主要是间日疟原虫引起的疟疾或结核病。患者还报告了一些不太常见的疾病,如利什曼病,甚至是在欧洲很少诊断出的疾病,如虱传回归热。观察到多重耐药微生物(MDRO)的携带率为31%,产超广谱β-内酰胺酶(ESBL)的大肠杆菌(n = 20)是最常见的MDRO。未发现产碳青霉烯酶肠杆菌科细菌的携带情况。

结论

欧洲当前的难民危机对医院提出了挑战,要求其快速识别并应对传染病以及MDRO的携带情况。迅速做出反应对于优化寻求庇护者传染病的治疗以最大限度地控制感染是必要的。

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