Benninga Marc A, Faure Christophe, Hyman Paul E, St James Roberts Ian, Schechter Neil L, Nurko Samuel
Pediatric Gastroenterology, Emma Children's Hospital / Academic Medical Center, Amsterdam, The Netherlands.
Pediatric Gastroenterology, Sainte-Justine Hospital, Montreal, Qc, Canada.
Gastroenterology. 2016 Feb 15. doi: 10.1053/j.gastro.2016.02.016.
In 2006, a consensus concerning functional gastrointestinal intestinal disorders (FGIDs) in infants and toddlers was described. At that time little evidence regarding epidemiology, pathophysiology, diagnostic work-up, treatment strategies and follow-up was available. Consequently the criteria for the clinical entities were more experience than evidence based. In the past decade, new insights have been gained in the different FGIDs in these age groups. Based on those, further revisions have been made to the criteria. The description of infant colic has been expanded to include criteria for the general pediatrician and specific criteria for researchers. The greatest change was the addition of a paragraph regarding the neurobiology of pain in infants and toddlers, including the understanding of the neurodevelopment of nociception and of the wide array of factors that may impact the pain experience.
2006年,关于婴幼儿功能性胃肠病(FGIDs)的一项共识被阐述。当时,关于流行病学、病理生理学、诊断检查、治疗策略及随访的证据很少。因此,临床实体的标准更多基于经验而非证据。在过去十年里,对于这些年龄组的不同功能性胃肠病有了新的认识。基于这些认识,对标准进行了进一步修订。婴儿腹绞痛的描述得到扩展,纳入了针对普通儿科医生的标准以及针对研究人员的特定标准。最大的变化是增加了一段关于婴幼儿疼痛神经生物学的内容,包括对伤害感受神经发育以及可能影响疼痛体验的众多因素的理解。