Yuce Ihsan, Turkeli Mehmet, Eren Suat, Levent Akin, Sade Recep, Kantarci Mecit
Department of Radiology, School of Medicine, Ataturk University, Erzurum, Turkey.
Department of Medical Oncology, School of Medicine, Ataturk University, Erzurum, Turkey.
Jpn J Radiol. 2016 Jul;34(7):503-7. doi: 10.1007/s11604-016-0548-0. Epub 2016 May 4.
To assess the tolerability of two different biopsy methods for thyroid nodules in a patient with nodular thyroid disease (NTD).
The study included 58 consecutive patients who had NTD from June 2014 to October 2015. Each patient had, at least, two thyroid nodules were located in two lobes. Parallel and perpendicular fine-needle aspirations (FNAs) were performed.
The mean maximum diameters of the assessed thyroid nodules using ultrasound (US) in parallel and perpendicular techniques were 23 ± 7 and 22 ± 6 mm, respectively. Nodule sizes were not significantly different (p > 0.05). For the parallel and perpendicular techniques, the mean numeric rating scale (NRS), verbal rating scale (VRS), and visual analog scale (VAS) values were 3.6 ± 1.9, 2.6 ± 1.1, and 17.2 ± 13 with 6.6 ± 1.7, 3.4 ± 0.5, and 37.8 ± 18, respectively. All these values were statistically significant (p < 0.001); there were no statistical differences between females and males in terms of three pain scales (p < 0.001).
Patients experienced significantly less pain when undergoing FNA of NTD using the parallel technique as opposed to the perpendicular technique. Therefore, we believe that FNA using parallel technique is preferable for NTD patients.
评估两种不同的甲状腺结节活检方法在结节性甲状腺疾病（NTD）患者中的耐受性。
该研究纳入了2014年6月至2015年10月期间连续的58例NTD患者。每位患者至少有两个位于两个叶的甲状腺结节。进行了平行和垂直细针穿刺抽吸（FNA）。
使用超声（US）评估的甲状腺结节在平行和垂直技术中的平均最大直径分别为23±7和22±6mm。结节大小无显著差异（p>0.05）。对于平行和垂直技术，平均数字评定量表（NRS）、言语评定量表（VRS）和视觉模拟量表（VAS）值分别为3.6±1.9、2.6±1.1和17.2±13以及6.6±1.7、3.4±0.5和37.8±18。所有这些值均具有统计学意义（p<0.001）；在三种疼痛量表方面，女性和男性之间无统计学差异（p<0.001）。
与垂直技术相比，患者在使用平行技术进行NTD的FNA时疼痛明显减轻。因此，我们认为平行技术的FNA对NTD患者更可取。
