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小儿高血压危象的评估与管理:高血压急症和高血压亚急症

Evaluation and management of pediatric hypertensive crises: hypertensive urgency and hypertensive emergencies.

作者信息

Patel Nirali H, Romero Sarah K, Kaelber David C

机构信息

Division of Emergency Medicine, Akron Children's Hospital, Akron, OH, USA.

Division of Emergency Medicine, Rainbow Babies and Children's Hospital, Cleveland, OH, USA.

出版信息

Open Access Emerg Med. 2012 Sep 5;4:85-92. doi: 10.2147/OAEM.S32809. eCollection 2012.

Abstract

Hypertension (HTN) in the pediatric population is estimated to have a world-wide prevalence of 2%-5%. As with adults, pediatric patients with HTN can present with hypertensive crises include hypertensive urgency and hypertensive emergencies. However, pediatric blood pressure problems have a greater chance of being from secondary causes of HTN, as opposed to primary HTN, than in adults. Thorough evaluation of a child with a hypertensive emergency includes accurate blood pressure readings, complete and focused symptom history, and appropriate past medical, surgical, and family history. Physical exam should include height, weight, four-limb blood pressures, a general overall examination and especially detailed cardiovascular and neurological examinations, including fundoscopic examination. Initial work-up should typically include electrocardiography, chest X-ray, serum chemistries, complete blood count, and urinalysis. Initial management of hypertensive emergencies generally includes the use of intravenous or oral antihypertensive medications, as well as appropriate, typically outpatient, follow-up. Emergency department goals for hypertensive crises are to (1) safely lower blood pressure, and (2) treat/minimize acute end organ damage, while (3) identifying underlying etiology. Intravenous antihypertensive medications are the treatment modality of choice for hypertensive emergencies with the goal of reducing systolic blood pressure by 25% of the original value over an 8-hour period.

摘要

据估计,小儿高血压(HTN)在全球范围内的患病率为2%-5%。与成人一样,患有高血压的儿科患者可能会出现高血压危象,包括高血压急症和高血压亚急症。然而,与成人相比,儿科血压问题由继发性高血压病因引起的可能性比原发性高血压更大。对患有高血压急症的儿童进行全面评估包括准确测量血压、完整且有重点的症状史,以及适当的既往病史、手术史和家族史。体格检查应包括身高、体重、四肢血压、全面的整体检查,尤其是详细的心血管和神经系统检查,包括眼底镜检查。初始检查通常应包括心电图、胸部X线、血清化学检查、全血细胞计数和尿液分析。高血压急症的初始治疗通常包括使用静脉或口服抗高血压药物,以及适当的、通常为门诊的随访。急诊科对高血压危象的目标是:(1)安全降低血压,(2)治疗/最小化急性终末器官损伤,同时(3)确定潜在病因。静脉注射抗高血压药物是高血压急症的首选治疗方式,目标是在8小时内将收缩压降至原始值的25%。

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