Mohammad-Hoseyni Ali, Pirmoradian-Najafabadi Maryam, Ashnagar Sajjad, Nokhbatolfoghahaei Hanieh, Fekrazad Reza
Postgraduate Student, Department of Orthodontics, School of Dentistry, Shahed University, Tehran, Iran.
PhD Candidate, Department of Dental Biomaterials, School of Dentistry, Research Center for Science and Technology in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
J Dent (Tehran). 2015 Sep;12(9):655-61.
The purpose of this experimental study was to evaluate the efficacy of low level laser therapy (LLLT) for pain reduction after midpalatal expansion in rats.
Sixty male Sprague six-week old rats weighing 180±10g were divided into seven groups (two experimental groups of 24 rats and one control group of 12 rats). The experimental groups were subjected to expansion with or without LLLT. The health status of each rat was monitored starting seven days prior to the experiment and evaluated by regular body weight monitoring during the study period. Diode laser with 810nm wavelength and 100 mw output power was used. Laser therapy and body weight monitoring were performed on days 0, 2, 4, 6, 8, 10, 12 and 14. The data were analyzed by One-way repeated measures ANOVA.
The body weight of the experimental groups significantly decreased in the first two days because of the pain and difficult nutrition with the new appliance. Within the next two days, the body weight of all rats increased but this increase was significantly higher in the irradiated compared to the non-irradiated group. This significant improvement continued until day 14 and then between days 14 and 30 the rats gained weight similarly in the irradiated and control groups.
The study results showed that laser irradiated group continued to gain weight easier than the control group. This may be due to more efficient pain control due to laser irradiation after midpalatal expansion.
本实验研究的目的是评估低强度激光疗法（LLLT）对大鼠腭中缝扩展后减轻疼痛的疗效。
将60只6周龄、体重180±10g的雄性Sprague大鼠分为7组（两个实验组，每组24只大鼠；一个对照组，12只大鼠）。实验组接受有或无LLLT的扩展治疗。从实验前7天开始监测每只大鼠的健康状况，并在研究期间通过定期监测体重进行评估。使用波长810nm、输出功率100mw的二极管激光。在第0、2、4、6、8、10、12和14天进行激光治疗和体重监测。数据采用单因素重复测量方差分析。
由于新装置带来的疼痛和营养困难，实验组大鼠体重在前两天显著下降。在接下来的两天里，所有大鼠体重均增加，但与未照射组相比，照射组体重增加更为显著。这种显著改善持续到第14天，然后在第14天至30天期间，照射组和对照组大鼠体重增加情况相似。
研究结果表明，激光照射组比对照组更容易持续增重。这可能是由于腭中缝扩展后激光照射能更有效地控制疼痛。
