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腹腔镜远端胰腺切除术:三级中心的学习曲线与经验

Laparoscopic Distal Pancreatectomy: Learning Curve and Experience in a Tertiary Center.

作者信息

Nachmany Ido, Pencovich Niv, Ben-Yehuda Amir, Lahat Guy, Nakache Richard, Goykhman Yaacov, Lubezky Nir, Klausner Joseph M

机构信息

Division of General Surgery, Department of General Surgery B, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University , Tel-Aviv, Israel .

出版信息

J Laparoendosc Adv Surg Tech A. 2016 Jun;26(6):470-4. doi: 10.1089/lap.2016.0098. Epub 2016 May 5.

Abstract

BACKGROUND

Although laparoscopic distal pancreatectomy (LDP) is gradually recognized as a safe and effective alternative to open distal pancreatectomy (ODP), it is not yet widely accepted.

OBJECTIVE

We describe our experience, with emphasis on the learning curve of LDP.

METHODS

Patients who underwent distal pancreatectomy (DP) between January 2011 and August 2014 were included. Operative and postoperative parameters, as well as pathology reports were evaluated.

RESULTS

Thirty-nine and 41 patients underwent LDP and ODP, respectively. The mean age and gender distribution were comparable between groups. In six patients (15.4%), a conversion to open surgery was indicated. Operating time and intraoperative blood transfusion rates were comparable between groups. One patient of the LDP group died postoperatively. Postoperative complications were comparable with similar Dindo-Clavien (DC) score. Length of stay (LOS) was shorter following LDP (8.15 ± 4.68 versus 11.3 ± 6.3 days, P = .014). Patients selected to have LDP had larger lesions compared to those who underwent ODP (4.59 ± 4.23 versus 3 ± 2.52 cm, respectively, P = .048). R0 resection rates between the groups were comparable (92.3% in LDP versus 97.5% in ODP) as well as lymph node (LN) harvest (6.4 ± 6.4 LN in LDP versus 7.6 ± 6.6 LN in ODP). Following the 17th patient, LDP operative time decreased by more than 35 minutes, no conversions were done, no blood transfusion was needed, and the LOS was shortened by over 2 days.

CONCLUSIONS

Short learning curve, shorter LOS, and satisfactory short-term oncological outcome place LDP as an attractive alternative for selected patients requiring DP.

摘要

背景

尽管腹腔镜远端胰腺切除术(LDP)逐渐被认为是开放性远端胰腺切除术(ODP)的一种安全有效的替代方法,但尚未被广泛接受。

目的

我们描述我们的经验,重点是LDP的学习曲线。

方法

纳入2011年1月至2014年8月期间接受远端胰腺切除术(DP)的患者。评估手术和术后参数以及病理报告。

结果

分别有39例和41例患者接受了LDP和ODP。两组之间的平均年龄和性别分布具有可比性。6例患者(15.4%)转为开放手术。两组之间的手术时间和术中输血率具有可比性。LDP组有1例患者术后死亡。术后并发症与相似的Dindo-Clavien(DC)评分相当。LDP后的住院时间(LOS)较短(8.15±4.68天对11.3±6.3天,P = 0.014)。与接受ODP的患者相比,选择进行LDP的患者病变更大(分别为4.59±4.23厘米对3±2.52厘米,P = 0.048)。两组之间的R0切除率相当(LDP组为92.3%,ODP组为97.5%),淋巴结(LN)清扫数量也相当(LDP组为6.4±6.4个LN,ODP组为7.6±6.6个LN)。在第17例患者之后,LDP手术时间减少了超过35分钟,没有转为开放手术,不需要输血,住院时间缩短了超过2天。

结论

学习曲线短、住院时间短以及短期肿瘤学结果令人满意,使LDP成为需要DP的特定患者的有吸引力的替代方法。

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