Howard N, Mounier-Jack S, Gallagher K E, Kabakama S, Griffiths U K, Feletto M, LaMontagne D S, Burchett H E D, Watson-Jones D
a London School of Hygiene and Tropical Medicine , Department of Global Health and Development , Tavistock Place, London , UK.
b London School of Hygiene and Tropical Medicine , Clinical Research Department , Keppel St, London , UK.
Hum Vaccin Immunother. 2016 Sep;12(9):2475-7. doi: 10.1080/21645515.2016.1178433. Epub 2016 May 9.
Demonstration projects or pilots of new public health interventions aim to build learning and capacity to inform country-wide implementation. Authors examined the value of HPV vaccination demonstration projects and initial national programmes in low-income and lower-middle-income countries, including potential drawbacks and how value for national scale-up might be increased. Data from a systematic review and key informant interviews, analyzed thematically, included 55 demonstration projects and 8 national programmes implemented between 2007-2015 (89 years' experience). Initial demonstration projects quickly provided consistent lessons. Value would increase if projects were designed to inform sustainable national scale-up. Well-designed projects can test multiple delivery strategies, implementation for challenging areas and populations, and integration with national systems. Introduction of vaccines or other health interventions, particularly those involving new target groups or delivery strategies, needs flexible funding approaches to address specific questions of scalability and sustainability, including learning lessons through phased national expansion.
新的公共卫生干预措施示范项目或试点旨在积累经验和提升能力，为在全国范围内实施提供依据。作者研究了低收入和中低收入国家人乳头瘤病毒（HPV）疫苗接种示范项目及初期国家项目的价值，包括潜在弊端以及如何提高国家推广的价值。通过系统综述和关键信息人访谈收集的数据，经主题分析，涵盖了2007年至2015年间实施的55个示范项目和8个国家项目（共89年的经验）。初期示范项目迅速提供了一致的经验教训。如果项目旨在为可持续的国家推广提供依据，其价值将会增加。精心设计的项目可以测试多种交付策略、针对具有挑战性的地区和人群进行实施，以及与国家系统整合。引入疫苗或其他卫生干预措施，特别是那些涉及新目标群体或交付策略的措施，需要灵活的资金筹集方式来解决可扩展性和可持续性的具体问题，包括通过分阶段的国家推广吸取经验教训。
