类风湿性关节炎患者滑液中蛋白质羰基含量增加。
Increased carbonyl content of proteins in synovial fluid from patients with rheumatoid arthritis.
作者信息
Chapman M L, Rubin B R, Gracy R W
机构信息
Department of Biochemistry, University of North Texas 76107-2690.
出版信息
J Rheumatol. 1989 Jan;16(1):15-8.
PMID:2716005
Abstract
The carbonyl content of proteins in the synovial fluid (SF) of patients with rheumatoid arthritis was significantly (p less than or equal to 0.10) elevated over levels in the SF of patients with osteoarthritis (OA). Other indicators of oxidative damage including catalse, ceruloplasmin, ferritin and superoxide dismutase also showed statistically significant differences (p less than or equal to 0.05) compared to patients with OA.
摘要
类风湿性关节炎患者滑液（SF）中蛋白质的羰基含量比骨关节炎（OA）患者滑液中的羰基含量显著升高（p≤0.10）。与OA患者相比，包括过氧化氢酶、铜蓝蛋白、铁蛋白和超氧化物歧化酶在内的其他氧化损伤指标也显示出统计学上的显著差异（p≤0.05）。
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