Oppert M
Klinik für Notfall- und Intensivmedizin, Klinikum Ernst von Bergmann, Charlottenstraße 72, 14467, Potsdam, Deutschland.
Med Klin Intensivmed Notfmed. 2016 May;111(4):290-4. doi: 10.1007/s00063-016-0162-z. Epub 2016 May 9.
Sepsis is still the leading cause of mortality in noncardiac intensive care units. The new definition of sepsis emphasizes the importance of organ dysfunction. The Sepsis-related Organ Failure Assessment (SOFA) score is an indicator for organ dysfunction. The diagnosis of sepsis is for the most part made on clinical parameters with an altered mental status being a very sensitive indicator. Microbiological work-up is essential and two sets of blood cultures are the recommended minimum. Management includes prompt initiation of adequate antibiotic treatment and swift fluid resuscitation. Overinfusion is to be avoided as this itself can have a negative impact on patient outcome.
脓毒症仍然是非心脏重症监护病房死亡的主要原因。脓毒症的新定义强调了器官功能障碍的重要性。脓毒症相关器官功能衰竭评估（SOFA）评分是器官功能障碍的一个指标。脓毒症的诊断大多基于临床参数，精神状态改变是一个非常敏感的指标。微生物学检查至关重要，推荐至少采集两套血培养标本。治疗包括迅速开始适当的抗生素治疗和快速液体复苏。应避免过度输液，因为这本身可能对患者的预后产生负面影响。
