Mandrell Joshua
Division of Dermatology, Loyola University Medical Center, Maywood, Illinois, USA.
Cutis. 2016 Apr;97(4):E15-8.
Onychomatricoma (OM) is a rare tumor originating from the nail matrix. Fingernail involvement is twice as common as toenail involvement. Onychomatricoma is the only tumor that actively produces a nail plate. Clinically, it presents with yellow discoloration along the entire nail plate, proximal splinter hemorrhages, and a tendency toward transverse overcurvature of the nail plate with prominent longitudinal ridging. We report a rare case of OM in which the etiology was associated with trauma. Onychomycosis can be present, which may serve as a predisposing factor or be secondary to the deformed nail plate. Histologically, the tumor is fibroepithelial or biphasic with stromal and epithelial components. Onychomatricoma has been further classified into 3 types, including unguioblastoma, unguioblastic fibroma, and atypical unguioblastic fibroma. Our case represents the unguioblastic fibroma type.
甲母质瘤(OM)是一种起源于甲母质的罕见肿瘤。累及手指甲的情况比累及脚趾甲的情况常见两倍。甲母质瘤是唯一能主动产生甲板的肿瘤。临床上,它表现为整个甲板发黄、近端甲下出血,以及甲板向横向过度弯曲并伴有明显纵嵴的倾向。我们报告一例罕见的甲母质瘤病例,其病因与创伤有关。可能存在甲癣,它可能是一个易感因素,也可能继发于变形的甲板。组织学上,肿瘤为纤维上皮性或双相性,有间质和上皮成分。甲母质瘤已进一步分为3种类型,包括成甲细胞瘤、成甲细胞纤维瘤和非典型成甲细胞纤维瘤。我们的病例属于成甲细胞纤维瘤类型。