Department of Dermatology, Faculty of Medicine, University of Chile, Santiago.
Department of Dermatology, Faculty of Medicine, Pontifical Catholic University of Chile, Santiago, Chile.
Acta Biomed. 2021 Apr 30;92(S1):e2021158. doi: 10.23750/abm.v92iS1.9519.
Onychomatricoma is a rare subungual tumor composed of stroma and nail matrix-like epithelium. Only seven cases of the pigmented variant have been reported in the literature.
We present a 62-year-old male patient with a 2-years history of a single fingernail thickening, deformation, and hyperpigmentation. He had been treated for onychomycosis, without improvement. Due to the increasing hyperpigmentation, and to rule out tumoral entities, including melanoma, a color Doppler ultrasound examination of the nail was requested, which showed a hypoechoic tumor of the nail matrix and bed, with hyperechogenic linear images inside, suggesting the diagnosis of onychomatricoma. Onychectomy and partial matricectomy were performed. Histological evaluation confirmed the diagnosis of onychomatricoma. Discusion and conclusion: Histological evaluation is the gold standard for the diagnosis of onychomatricoma. However, ultrasonography represents an easily accessible, non-invasive diagnostic tool for the initial evaluation of these tumors, especially in unsuspected atypical clinical presentations.
甲床基质瘤是一种罕见的发生于甲下的肿瘤，由基质和甲母质样上皮组成。文献中仅报道了 7 例色素性变异型。
我们报告了 1 例 62 岁男性患者，其病史为单个指甲增厚、变形和色素沉着 2 年。他曾因甲真菌病接受治疗，但无改善。由于色素沉着增加，并为排除包括黑色素瘤在内的肿瘤性病变，行甲彩色多普勒超声检查，显示甲母质和床的低回声肿瘤，内部有高回声线性图像，提示甲床基质瘤的诊断。行甲切除术和部分甲母质切除术。组织学评估证实了甲床基质瘤的诊断。讨论和结论：组织学评估是甲床基质瘤的金标准。然而，超声检查是这些肿瘤初始评估的一种易于获得、非侵入性的诊断工具，尤其是在可疑的非典型临床表现中。
