Schwarz Frank, Golubovic Vladimir, Mihatovic Ilja, Becker Jürgen
Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
J Clin Periodontol. 2016 Sep;43(9):797-803. doi: 10.1111/jcpe.12579. Epub 2016 Jun 25.
To assess the efficacy of periodontally diseased tooth roots used as autografts for lateral ridge augmentation and two-stage early osseointegration of titanium implants.
Ligature-induced periodontitis lesions were established at the maxillary premolars in n = 8 foxhounds. Extracted, scaled and root planed pre-molar roots (PM-P) as well as retromolar cortical autogenous bone (AB) blocks were used for horizontal ridge augmentation of mandibular chronic-type defects. At 12 weeks, titanium implants were inserted and left to heal for another 3 weeks. Histological analyses included crestal ridge width (CW), augmented area (AA) and bone-to-implant contact (BIC).
Both PM-P and AB grafts were gradually organized and replaced by newly formed bone. Median CW (PM-P: 3.83 versus AB: 3.67 mm), AA (PM-P: 10.18 versus AB: 9.82 mm(2) ) and BIC (PM-P: 50.00% versus AB: 35.21%) values did not reach statistical significance between groups (p > 0.05, respectively). Histologically, PM-P grafts were not associated with any inflammatory cell infiltrates.
PM-P autografts may reveal a structural and biological potential to serve as an alternative autograft to AB.
评估患牙周病的牙根作为自体骨移植材料用于侧方牙槽嵴增高及钛种植体两阶段早期骨结合的疗效。
在8只猎狐犬的上颌前磨牙处建立结扎诱导的牙周炎病变。将拔除的、刮治并根面平整后的前磨牙牙根（PM-P）以及磨牙后皮质自体骨（AB）块用于下颌慢性型缺损的水平牙槽嵴增高。12周时植入钛种植体，再愈合3周。组织学分析包括嵴顶宽度（CW）、增高面积（AA）和骨-种植体接触（BIC）。
PM-P和AB移植骨均逐渐被新形成的骨组织替代。两组间的CW中位数（PM-P：3.83对AB：3.67mm）、AA（PM-P：10.18对AB：9.82mm²）和BIC（PM-P：50.00%对AB：35.21%）值均未达到统计学显著性（p均>0.05）。组织学上，PM-P移植骨未出现任何炎性细胞浸润。
PM-P自体骨移植可能显示出作为AB替代自体骨移植材料的结构和生物学潜力。
