Department of Oral Surgery and Implantology, Goethe University, Frankfurt, Germany.
Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
J Clin Periodontol. 2019 Apr;46(4):502-509. doi: 10.1111/jcpe.13090. Epub 2019 Mar 28.
To assess the influence of autoclavation on the efficacy of extracted tooth roots (TR) used for vertical alveolar ridge augmentation and two-stage osseointegration.
Maxillary premolars were randomly assigned to either autoclavation (TR-A) or were left untreated (TR-C) and used as block grafts for vertical alveolar ridge augmentation in both lower quadrants (n = 4 beagle dogs). At 12 weeks, titanium implants were inserted and left to heal for 3 weeks. Histological analyses considered vertical bone gain (BD-BC), augmented area (AA) and bone-to-implant contact (BIC) at vestibular (v) and oral (o) aspects.
Both TR-C and TR-A (exposures n = 3) grafts were associated with a replacement resorption and marked vertical bone gain. Median BD-BC (TR-C: 1.45 [v] to 1.62 mm [o] versus TR-A: 0.97 [v] to 1.79 mm [o]) and AA (TR-C: 0.64 [v] to 2.36 mm [o] versus TR-A: 0.22 [v] to 2.36 mm [o]) values were comparable in both groups. V BIC (TR-C: 49.32 [v] to 52.97% [o] versus TR-A: 25.34 [v] to 46.11% [o]) values were significantly higher in the TR-C group.
Both TR-C and TR-A grafts equally supported vertical alveolar ridge augmentation; however, osseointegration was partially facilitated in the TR-C group.
评估高压灭菌对用于垂直牙槽嵴增高和两阶段骨整合的拔出牙根（TR）疗效的影响。
上颌前磨牙随机分为高压灭菌组（TR-A）或未处理组（TR-C），并在下颌两个象限中用作垂直牙槽嵴增高的块状移植物（n=4 只比格犬）。在 12 周时，插入钛植入物并使其愈合 3 周。组织学分析考虑了颊侧（v）和舌侧（o）的垂直骨增加量（BD-BC）、增强区（AA）和骨-种植体接触（BIC）。
TR-C 和 TR-A（暴露 n=3）移植物均与替代吸收和明显的垂直骨增加有关。BD-BC 的中位数（TR-C：1.45[v]至 1.62mm [o]与 TR-A：0.97[v]至 1.79mm [o]）和 AA（TR-C：0.64[v]至 2.36mm [o]与 TR-A：0.22[v]至 2.36mm [o]）值在两组中相当。TR-C 组的 v BIC（TR-C：49.32[v]至 52.97% [o]与 TR-A：25.34[v]至 46.11% [o]）值明显更高。
TR-C 和 TR-A 移植物均同等支持垂直牙槽嵴增高；然而，在 TR-C 组中部分促进了骨整合。
