Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
Department of Orthodontics, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
J Clin Periodontol. 2016 Apr;43(4):345-53. doi: 10.1111/jcpe.12481. Epub 2016 Mar 17.
To assess the efficacy of tooth roots used as autografts for lateral ridge augmentation and two-stage early osseointegration of titanium implants.
MATERIAL & METHODS: The maxillary premolars were randomly assigned to either endodontic therapy (PM-E) or were left untreated (PM-C). Retromolar cortical autogenous bone (AB) blocks served as controls. PM-E/PM-C and AB were used for ridge augmentation at chronic-type defects in both lower quadrants (n = 8 foxhounds). At 12 weeks, titanium implants were inserted and left to heal for another 3 weeks. Histological analyses considered crestal ridge width (CW); augmented area (AA) and bone-to-implant contact (BIC).
Both PM and AB grafts (exposures: AB = 3; PM-C = 4; PM-E = 7) were gradually involved in the bone remodelling process and associated with a replacement resorption. Median CW (PM-C: 2.70 versus AB: 3.30 mm; PM-E: 2.96 versus AB: 3.35 mm), AA (PM-C: 7.55 versus AB: 8.56 mm(2) ; PM-E: 11.20 versus AB: 6.60 mm(2) ) and BIC (PM-C: 36.96 mm versus AB: 64.10%; PM-E: 50.79 versus AB: 32.53%) values were comparable in both PM and AB groups (p > 0.05, respectively).
Extracted tooth roots revealed a structural and biological potential to serve as an alternative autograft to autogenous bone. A higher exposure rate may be expected when using endodontically treated teeth.
评估自体牙根用于侧向嵴增高和钛种植体两阶段早期骨整合的疗效。
上颌前磨牙随机分为牙髓治疗组（PM-E）或未治疗组（PM-C）。磨牙后皮质自体骨（AB）块作为对照。PM-E/PM-C 和 AB 在下颌四个象限的慢性型缺损中用于嵴增高（n=8 只猎狐犬）。12 周时，插入钛种植体并再愈合 3 周。组织学分析考虑了牙槽嵴宽度（CW）；增高区（AA）和骨-种植体接触（BIC）。
PM 和 AB 移植物（暴露：AB=3；PM-C=4；PM-E=7）均逐渐参与骨重塑过程，并伴有替代吸收。CW 的中位数（PM-C：2.70 与 AB：3.30mm；PM-E：2.96 与 AB：3.35mm）、AA（PM-C：7.55 与 AB：8.56mm²；PM-E：11.20 与 AB：6.60mm²）和 BIC（PM-C：36.96%与 AB：64.10%；PM-E：50.79%与 AB：32.53%）在 PM 和 AB 两组中均无差异（分别为 p>0.05）。
拔出的牙根具有作为自体骨替代物的结构和生物学潜力。使用牙髓治疗的牙齿可能会有更高的暴露率。
