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一名复发性尿路感染患者的序列型131的H30Rx亚克隆中产生CTX-M-15的大肠杆菌菌株的全基因组序列，与该患者妹妹的致命性泌尿道感染分离株密切相关。

Complete Genome Sequence of a CTX-M-15-Producing Escherichia coli Strain from the H30Rx Subclone of Sequence Type 131 from a Patient with Recurrent Urinary Tract Infections, Closely Related to a Lethal Urosepsis Isolate from the Patient's Sister.

作者信息

Johnson Timothy J, Aziz Maliha, Liu Cindy M, Sokurenko Evgeni, Kisiela Dagmara I, Paul Sandip, Andersen Paal, Johnson James R, Price Lance B

机构信息

Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA.

Department of Environmental and Occupational Health, George Washington University, Washington, District of Columbia, USA Division of Pathogen Genomics, Translational Genomics Research Institute (TGen), Flagstaff, Arizona, USA

出版信息

Genome Announc. 2016 May 12;4(3):e00334-16. doi: 10.1128/genomeA.00334-16.

DOI:10.1128/genomeA.00334-16
PMID:27174264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4866839/
Abstract

We report here the complete genome sequence, including five plasmid sequences, of Escherichia coli sequence type 131 (ST131) strain JJ1887. The strain was isolated in 2007 in the United States from a patient with recurrent cystitis, whose caregiver sister died from urosepsis caused by a nearly identical strain.

摘要

我们在此报告大肠杆菌序列类型131（ST131）菌株JJ1887的完整基因组序列，包括五条质粒序列。该菌株于2007年在美国从一名复发性膀胱炎患者体内分离得到，其护理人员姐姐死于由一株几乎相同的菌株引起的泌尿道感染。

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本文引用的文献

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A new clone sweeps clean: the enigmatic emergence of Escherichia coli sequence type 131.一个新的克隆群体彻底席卷：大肠杆菌序列类型131的神秘出现。
Antimicrob Agents Chemother. 2014 Sep;58(9):4997-5004. doi: 10.1128/AAC.02824-14. Epub 2014 May 27.
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In silico detection and typing of plasmids using PlasmidFinder and plasmid multilocus sequence typing.使用质粒查找工具（PlasmidFinder）和质粒多位点序列分型进行质粒的电子检测和分型
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Prokka: rapid prokaryotic genome annotation.Prokka：快速的原核生物基因组注释。
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The epidemic of extended-spectrum-β-lactamase-producing Escherichia coli ST131 is driven by a single highly pathogenic subclone, H30-Rx.产超广谱β-内酰胺酶大肠杆菌 ST131 流行是由一个单一的高致病性亚克隆 H30-Rx 驱动的。
mBio. 2013 Dec 17;4(6):e00377-13. doi: 10.1128/mBio.00377-13.
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Complete Genome Sequence of the Epidemic and Highly Virulent CTX-M-15-Producing H30-Rx Subclone of Escherichia coli ST131.产CTX-M-15的大肠杆菌ST131流行且高毒力H30-Rx亚克隆的全基因组序列
Genome Announc. 2013 Dec 5;1(6):e00988-13. doi: 10.1128/genomeA.00988-13.
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Abrupt emergence of a single dominant multidrug-resistant strain of Escherichia coli.大肠杆菌单一优势耐药株的突然出现。
J Infect Dis. 2013 Mar 15;207(6):919-28. doi: 10.1093/infdis/jis933. Epub 2013 Jan 3.
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Identification of acquired antimicrobial resistance genes.获得性抗菌耐药基因的鉴定。
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