Liu Shao-ying, Wang Tong, Xie Juan, Zhi Xin-yue
Tianjin Jinghai Centers for Disease Control and Prevention,Tianjin 301600,China.
Department of Epidemiology and Biostatistics,School of Public Health,Tianjin Medical University,Tianjin 300070,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2016 Apr;38(2):210-6. doi: 10.3881/j.issn.1000-503X.2016.02.015.
To analyze the status of lipid metabolism and the relationship between low birth body mass and lipid metabolism disorders in adolescents with different economic and cultural backgrounds.
Totally 1700 adolescents from urban and rural areas aged 12-18 years were selected in 2013. The lipid profiles were determined, and a questionnaire-based survey was conducted.
Among normal birth body mass adolescents, girls obtained a high density lipoprotein in both urban and rural areas, low density lipoprotein cholesterol level was higher for city girls, rural boys and urban girls obtained higher total cholesterol level, the differences all reached statistical significance. While among the low birth body mass adolescents, higher level of total cholesterol for urban boys was detected, with statistically significance. When compared between rural and urban areas, high density lipoprotein cholesterol level for urban adolescents was lower in normal birth body mass adolescents, while total cholesterol level for urban adolescents was higher, both with statistically significance. While the comparison between different birth body mass adolescents suggested that the normal birth body mass adolescents obtained a higher high density lipoprotein cholesterol, low density lipoprotein cholesterol, triglyceride and total cholesterol level. When analyze the influenced factors of disorder of lipid metabolism, the Results suggest that low birth body mass, maternal pregnancy body mass increasing, lipid homeostasis family history, absence of breakfast, unhealthy snack habit, abnormal of systolic blood pressure and pulse pressure increasing were related to the occurrence of dyslipidemia.
Low birth body mass is related with lipid metabolism in early puberty. Low birth body mass, family history of abnormal lipid metabolism, and poor diet habits can increase the risk of abnormal lipid metabolism in puberty.
分析不同经济文化背景青少年的脂质代谢状况以及低出生体重与脂质代谢紊乱之间的关系。
2013年选取了1700名年龄在12 - 18岁的城乡青少年。测定其血脂谱,并进行问卷调查。
在正常出生体重的青少年中,城乡女孩的高密度脂蛋白、城市女孩的低密度脂蛋白胆固醇水平较高,农村男孩和城市女孩的总胆固醇水平较高,差异均有统计学意义。而在低出生体重的青少年中,城市男孩的总胆固醇水平较高,差异有统计学意义。城乡比较显示,正常出生体重青少年中城市青少年的高密度脂蛋白胆固醇水平较低,而总胆固醇水平较高,均有统计学意义。不同出生体重青少年之间的比较表明,正常出生体重青少年的高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、甘油三酯和总胆固醇水平较高。在分析脂质代谢紊乱的影响因素时,结果表明低出生体重、母亲孕期体重增加、脂质稳态家族史、不吃早餐、不健康的零食习惯、收缩压异常和脉压升高与血脂异常的发生有关。
低出生体重与青春期早期的脂质代谢有关。低出生体重、脂质代谢异常家族史和不良饮食习惯会增加青春期脂质代谢异常的风险。