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希腊青少年的血脂及其与饮食、肥胖和社会经济因素的关系。

Blood lipids in Greek adolescents and their relation to diet, obesity, and socioeconomic factors.

作者信息

Petridou E, Malamou H, Doxiadis S, Pantelakis S, Kanellopoulou G, Toupadaki N, Trichopoulou A, Flytzani V, Trichopoulos D

机构信息

Department of Hygiene and Epidemiology, Athens University Medical School, Greece.

出版信息

Ann Epidemiol. 1995 Jul;5(4):286-91. doi: 10.1016/1047-2797(94)00094-a.

Abstract

A study of blood lipid levels in adolescent students in rural and urban areas of Greece was undertaken. Blood samples were drawn from 307 adolescents aged 12 to 18 years attending two rural and two urban high schools of different socioeconomic level (urban/lower, urban/higher). Obesity among adolescents had statistically significant detrimental effects on the lipids profile, being associated with higher total and low-density-lipoprotein (LDL) cholesterol and lower high-density-lipoprotein (HDL) cholesterol levels. Adolescents living in urban areas had substantially and significantly higher levels of total and LDL cholesterol, but among urban residents, higher socioeconomic status was associated with lower levels of total and LDL cholesterol. There was no clear evidence that total, LDL, and HDL cholesterol levels were substantially affected by qualitative aspects of diet as evaluated through a food frequency questionnaire. The results of this study indicate that the traditional Mediterranean pattern of living and eating in the rural areas of Greece is associated with a favorable lipid profile in adolescents, which may explain the very low incidence of coronary heart disease (CHD) in these areas. In urban areas lipid profiles are satisfactory in children of high socioeconomic status but unfavorable in children of low- to middle-class families, which are known to be at higher risk for CHD.

摘要

对希腊城乡地区青少年学生的血脂水平进行了一项研究。从两所不同社会经济水平(城市/较低、城市/较高)的农村高中和两所城市高中的307名12至18岁青少年中采集了血样。青少年肥胖对血脂谱有统计学上的显著不利影响,与较高的总胆固醇和低密度脂蛋白(LDL)胆固醇以及较低的高密度脂蛋白(HDL)胆固醇水平相关。生活在城市地区的青少年的总胆固醇和LDL胆固醇水平显著更高,但在城市居民中,较高的社会经济地位与较低的总胆固醇和LDL胆固醇水平相关。没有明确证据表明通过食物频率问卷评估的饮食质量方面会对总胆固醇、LDL胆固醇和HDL胆固醇水平产生实质性影响。这项研究的结果表明,希腊农村地区传统的地中海生活和饮食方式与青少年良好的血脂谱相关,这可能解释了这些地区冠心病(CHD)发病率极低的原因。在城市地区,社会经济地位高的儿童血脂谱令人满意,但中低收入家庭的儿童血脂谱不佳,而这些家庭已知患冠心病的风险更高。

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