Department of Medicine, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.
Ethn Dis. 2013 Summer;23(3):374-8.
To compare the serum lipids levels, prevalence of dyslipidaemia, and adiposity of rural versus urban dwellers in Sokoto, Nigeria.
A cross-sectional study was conducted in both rural and urban areas of Sokoto, Nigeria. One hundred participants were recruited using a multi-stage sampling method. Demographic data and anthropometric measurements were obtained. Fasting blood was drawn for assessment of total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL-C) and low-density lipoprotein (LDL-C) cholesterol. The classification of dyslipidemia was based on the National Cholesterol Education Program-Adult Treatment Panel guidelines.
The (mean [SD]) waist circumference of the urban participants (83.8 [9.5] cm) was significantly higher than the rural participants (79.2 [11.2] cm) (P = .030). The mean BMI of the urban participants (23.9 [3.9] kg/m2) was higher than the rural participants (22.2 [3.7] kg/m2) (P = .09). The mean TC was significantly higher in urban (175.9 [49.6] mg/dL) than rural participants (148.3 [24.3] mg/dL) P < .001. Mean serum LDL-C, and TG concentrations were higher in the urban than rural participants but the difference was not statistically significant. Mean serum HDL-C was also insignificantly higher in the rural (51.1 [7.9] mg/dL) than in urban participants (50.2 [11.7] mg/dL) (P = .64). The most frequent dyslipidemia was abnormally low HDL-C (13%) and this was more common in the urban participants (16%) than in rural participants (10%).
This study demonstrated that compared to the rural dwellers, the urban dweller were more likely to be obese and had higher frequency of adverse plasma lipid profile. This may have implications for rural-urban patterns of lipid related cardiovascular disease.
比较尼日利亚索科托农村和城市居民的血清脂质水平、血脂异常患病率和肥胖情况。
本研究在尼日利亚索科托的农村和城市地区进行了一项横断面研究。采用多阶段抽样方法招募了 100 名参与者。收集了人口统计学数据和人体测量学数据。抽取空腹血样以评估总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白（HDL-C）和低密度脂蛋白（LDL-C）胆固醇。血脂异常的分类基于国家胆固醇教育计划-成人治疗小组指南。
城市参与者的（平均[标准差]）腰围（83.8[9.5]cm）明显高于农村参与者（79.2[11.2]cm）（P=0.030）。城市参与者的平均 BMI（23.9[3.9]kg/m2）高于农村参与者（22.2[3.7]kg/m2）（P=0.09）。城市参与者的平均 TC（175.9[49.6]mg/dL）明显高于农村参与者（148.3[24.3]mg/dL）（P<0.001）。城市参与者的血清 LDL-C 和 TG 浓度也高于农村参与者，但差异无统计学意义。农村参与者的血清 HDL-C 也略高于城市参与者（51.1[7.9]mg/dL 比 50.2[11.7]mg/dL）（P=0.64）。最常见的血脂异常是异常低的 HDL-C（13%），且在城市参与者（16%）中比农村参与者（10%）更为常见。
与农村居民相比，城市居民更可能肥胖，且血脂谱不良的发生率更高。这可能对城乡脂质相关心血管疾病模式有影响。
