Weise K, Evers K H
Berufsgenossenschaftliche Unfallklinik Tübingen.
Aktuelle Traumatol. 1988 Oct;18(5):219-25.
Local treatment of difficult wounds with TCDO, a chemically stable, water-soluble compound containing oxygen in a chlorite matrix, is supposed to increase the pO2 in hypoxic wound tissue and to amplify physiological responses of phagocytes in wounds. 21 patients were assigned to two groups, treated by TCDO impregnated dressings twice a day or by TCDO combined with temporary skin coverage Epigard. Daily records of the state of the wounds with regard to exudation, wound cleansing, formation of granulation tissue and epithelisation demonstrated the therapeutic effect of TCDO in the treatment of complicated wounds when primary surgical debridement was sufficient.
采用TCDO对难愈合伤口进行局部治疗，TCDO是一种化学性质稳定的水溶性化合物，其亚氯酸盐基质中含有氧，有望提高缺氧伤口组织中的pO2，并增强伤口中吞噬细胞的生理反应。21名患者被分为两组，分别接受每天两次的TCDO浸渍敷料治疗或TCDO联合临时皮肤覆盖物Epigard治疗。每天记录伤口在渗出、伤口清洁、肉芽组织形成和上皮化方面的状态，结果表明，当初始手术清创充分时，TCDO对复杂伤口具有治疗效果。
