Zenker W, Thiede A, Dommes M, Ullmann U
Chirurg. 1986 May;57(5):334-9.
In a controlled study on the treatment of wound-healing impairments 29 patients underwent local treatment with TCDO (Oxoferin) while Beta-isodona was used in 31 cases. Regarding the criterion of reducing the wound area, i.e. epithelization, a highly significant superiority of Oxoferin could be demonstrated in the treatment of complicated wounds. The evaluation of the state of granulation, that was documented by a semiquantitative procedure, indicated that Oxoferin tends to be slightly superior. However, the following observations have to be emphasized: Oxoferin induces a development of granulation tissue on exposed tendons, bones, and fasciae and the granular tissue is of much better quality than after treatment with Betaisodona. Concerning its effect on the degree of contamination, Oxoferin proved to be at least as efficacious as the established and effective antiseptic Betaisodona. Both substances are tolerated well and the application is simple, they do not differ here.
在一项关于伤口愈合障碍治疗的对照研究中，29例患者接受了TCDO（奥索铁林）局部治疗，而31例患者使用了β-异杜那。关于减少伤口面积这一标准，即上皮形成，在复杂伤口治疗中，奥索铁林显示出高度显著的优越性。通过半定量程序记录的肉芽状态评估表明，奥索铁林往往略占优势。然而，必须强调以下观察结果：奥索铁林可促使暴露的肌腱、骨骼和筋膜上形成肉芽组织，且肉芽组织质量比使用β-异杜那治疗后要好得多。关于其对污染程度的影响，奥索铁林被证明至少与已确立且有效的防腐剂β-异杜那一样有效。两种物质耐受性良好且应用简单，在这方面没有差异。
