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J Clin Diagn Res. 2016 Apr;10(4):OD20-2. doi: 10.7860/JCDR/2016/16395.7678. Epub 2016 Apr 1.
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本文引用的文献

1
ACTH Stimulation Tests for the Diagnosis of Adrenal Insufficiency: Systematic Review and Meta-Analysis.用于诊断肾上腺皮质功能不全的促肾上腺皮质激素刺激试验:系统评价与荟萃分析
J Clin Endocrinol Metab. 2016 Feb;101(2):427-34. doi: 10.1210/jc.2015-1700. Epub 2015 Dec 9.
2
Hydrocortisone malabsorption due to polyethylene glycols (Macrogol 3350) in a girl with congenital adrenal insufficiency.一名先天性肾上腺皮质功能减退女孩因聚乙二醇(聚乙二醇3350)导致氢化可的松吸收不良。
Ital J Pediatr. 2014 Sep 26;40:78. doi: 10.1186/s13052-014-0078-2.
3
Adrenal insufficiency.肾上腺功能不全。
Lancet. 2014 Jun 21;383(9935):2152-67. doi: 10.1016/S0140-6736(13)61684-0. Epub 2014 Feb 4.
4
Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency.原发性肾上腺功能不全患者的诊断、治疗和随访共识声明。
J Intern Med. 2014 Feb;275(2):104-15. doi: 10.1111/joim.12162. Epub 2013 Dec 16.
5
Delay in diagnosis of adrenal insufficiency is a frequent cause of adrenal crisis.诊断肾上腺功能不全的延误是导致肾上腺危象的常见原因。
Int J Endocrinol. 2013;2013:482370. doi: 10.1155/2013/482370. Epub 2013 Jun 24.
6
A case of acute adrenal insufficiency unmasked during sunitinib treatment for metastatic renal cell carcinoma.索坦(舒尼替尼)治疗转移性肾细胞癌期间急性肾上腺功能不全被揭示 1 例。
Jpn J Clin Oncol. 2012 Aug;42(8):764-6. doi: 10.1093/jjco/hys070. Epub 2012 May 11.
7
Autoimmune hyperthyroidism due to secondary adrenal insufficiency: resolution with glucocorticoids.自身免疫性甲状腺功能亢进症继发于肾上腺皮质功能不全:糖皮质激素治疗后缓解。
Endocr Pract. 2011 Jan-Feb;17(1):85-90. doi: 10.4158/EP10069.CR.
8
Epidemiology of adrenal crisis in chronic adrenal insufficiency: the need for new prevention strategies.慢性肾上腺功能不全性肾上腺危象的流行病学:需要新的预防策略。
Eur J Endocrinol. 2010 Mar;162(3):597-602. doi: 10.1530/EJE-09-0884. Epub 2009 Dec 2.
9
Predisposing factors for adrenal insufficiency.肾上腺功能不全的诱发因素。
N Engl J Med. 2009 May 28;360(22):2328-39. doi: 10.1056/NEJMra0804635.
10
New onset Graves' disease as a cause of an adrenal crisis in an individual with panhypopituitarism: brief report.新发格雷夫斯病作为全垂体功能减退患者肾上腺危象的病因:简要报告
Thyroid Res. 2008 Nov 19;1(1):7. doi: 10.1186/1756-6614-1-7.

以原发性肾上腺皮质功能减退症反复肾上腺危象形式出现的格雷夫斯甲状腺毒症延迟诊断

Delayed Diagnosis of Graves' Thyrotoxicoisis Presenting as Recurrent Adrenal Crisis in Primary Adrenal Insufficiency.

作者信息

Naik Dukhabandhu, Jebasingh K Felix, Thomas Nihal

机构信息

Associate Professor, Department of Endocrinology, Diabetes and Metabolism, Christian Medical College , Vellore, Tamil Nadu, India .

Senior Registrar, Department of Endocrinology, Diabetes and Metabolism, Christian Medical College , Vellore, Tamil Nadu, India .

出版信息

J Clin Diagn Res. 2016 Apr;10(4):OD20-2. doi: 10.7860/JCDR/2016/16395.7678. Epub 2016 Apr 1.

DOI:10.7860/JCDR/2016/16395.7678
PMID:27190873
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4866171/
Abstract

Adrenal crisis is a potential life threatening complication. The common causes of adrenal crisis are infections, surgical stress and abrupt cessation of steroid medications. Endocrine causes like Graves' disease with thyrotoxicosis is one of the less common causes of an adrenal crisis. We report a 42-year-old female who presented with recurrent episodes of adrenal crisis due to delayed diagnosis of thyrotoxicosis. She was initially treated with Carbimazole followed by Radio-iodine ablation and currently she is euthyroid. Her adrenal insufficiency was initially treated with hydrocortisone during the time of adrenal crisis followed by Prednisolone 5 mg once daily in the morning along with fludrocortisone 50 mcg once daily. This case highlights the need for high index of suspicion and less common causes like thyrotoxicosis should be ruled out in patients with adrenal crisis.

摘要

肾上腺危象是一种潜在的危及生命的并发症。肾上腺危象的常见病因包括感染、手术应激和类固醇药物的突然停用。像伴有甲状腺毒症的格雷夫斯病这样的内分泌病因是肾上腺危象较不常见的病因之一。我们报告一名42岁女性,因甲状腺毒症诊断延迟而反复出现肾上腺危象发作。她最初接受甲巯咪唑治疗,随后进行放射性碘消融,目前甲状腺功能正常。她的肾上腺功能不全在肾上腺危象期间最初用氢化可的松治疗,随后每天早晨服用5毫克泼尼松龙以及每天服用50微克氟氢可的松。该病例强调了高度怀疑的必要性,对于肾上腺危象患者应排除像甲状腺毒症这样较不常见的病因。